| 06 May 1980 | Zone D | Glamorgan Under-25s v Worcestershire Under-25s | Sophia Gardens, Cardiff | Results |
| 19 May 1980 | Zone C | Kent Under-25s v Surrey Under-25s | HSBC Sports and Social Club, Beckenham | Results |
| 19 May 1980 | Zone B | Middlesex Under-25s v Leicestershire Under-25s | Corfton Road, Ealing | Results |
| 20 May 1980 | Zone D | Gloucestershire Under-25s v Warwickshire Under-25s | Seat Unique Stadium, Bristol | Results |
| 25 May 1980 | Zone D | Worcestershire Under-25s v Warwickshire Under-25s | Visit Worcestershire New Road, Worcester | Results |
| 02 Jun 1980 | Zone A | Nottinghamshire Under-25s v Yorkshire Under-25s | Trent Bridge, Nottingham | Results |
| 03 Jun 1980 | Zone A | Derbyshire Under-25s v Yorkshire Under-25s | Racecourse Ground, Derby | Results |
| 09 Jun 1980 | Zone C | Kent Under-25s v Sussex Under-25s | The Nevill Ground, Tunbridge Wells | Results |
| 09 Jun 1980 | Zone B | Leicestershire Under-25s v Middlesex Under-25s | Uptonsteel County Ground, Leicester | Results |
| 16 Jun 1980 | Zone D | Warwickshire Under-25s v Worcestershire Under-25s | Edgbaston, Birmingham | Results |
| 17 Jun 1980 | Zone C | Hampshire Under-25s v Kent Under-25s | County Ground, Southampton | Results |
| 17 Jun 1980 | Zone A | Lancashire Under-25s v Nottinghamshire Under-25s | Emirates Old Trafford, Manchester | Results |
| 17 Jun 1980 | Zone D | Warwickshire Under-25s v Gloucestershire Under-25s | Swans Nest Lane, Stratford-upon-Avon | Results |
| 17 Jun 1980 | Zone A | Yorkshire Under-25s v Derbyshire Under-25s | Headingley, Leeds | Results |
| 23 Jun 1980 | Zone D | Gloucestershire Under-25s v Glamorgan Under-25s | Seat Unique Stadium, Bristol | Results |
| 23 Jun 1980 | Zone A | Nottinghamshire Under-25s v Derbyshire Under-25s | Worksop College Ground, Worksop | Results |
| 23 Jun 1980 | Zone C | Surrey Under-25s v Kent Under-25s | The Kia Oval, Kennington | Results |
| 30 Jun 1980 | Zone B | Middlesex Under-25s v Northamptonshire Under-25s | The Paulin Ground, Winchmore Hill | Results |
| 30 Jun 1980 | Zone D | Worcestershire Under-25s v Gloucestershire Under-25s | Visit Worcestershire New Road, Worcester | Results |
| 30 Jun 1980 | Zone A | Yorkshire Under-25s v Lancashire Under-25s | Clifton Park, York | Results |
| 01 Jul 1980 | Zone D | Glamorgan Under-25s v Warwickshire Under-25s | Bulwark Ground, Chepstow | Results |
| 01 Jul 1980 | Zone A | Lancashire Under-25s v Derbyshire Under-25s | Emirates Old Trafford, Manchester | Results |
| 01 Jul 1980 | Zone A | Yorkshire Under-25s v Nottinghamshire Under-25s | The Circle, Hull | Results |
| 03 Jul 1980 | Zone B | Leicestershire Under-25s v Northamptonshire Under-25s | Uptonsteel County Ground, Leicester | Results |
| 04 Jul 1980 | Zone B | Northamptonshire Under-25s v Leicestershire Under-25s | County Ground, Northampton | Results |
| 07 Jul 1980 | Zone A | Nottinghamshire Under-25s v Lancashire Under-25s | Washpit Lane, Colston Bassett | Results |
| 07 Jul 1980 | Zone C | Sussex Under-25s v Kent Under-25s | Central Recreation Ground, Hastings | Results |
| 08 Jul 1980 | Zone A | Derbyshire Under-25s v Lancashire Under-25s | Racecourse Ground, Derby | Results |
| 08 Jul 1980 | Zone C | Sussex Under-25s v Hampshire Under-25s | Arundel Castle Cricket Club Ground, Arundel | Results |
| 11 Jul 1980 | Zone B | Middlesex Under-25s v Essex Under-25s | Woodside, Watford | Results |
| 14 Jul 1980 | Zone A | Derbyshire Under-25s v Nottinghamshire Under-25s | Racecourse Ground, Derby | Results |
| 14 Jul 1980 | Zone C | Hampshire Under-25s v Surrey Under-25s | County Ground, Southampton | Results |
| 14 Jul 1980 | Zone B | Leicestershire Under-25s v Essex Under-25s | Uptonsteel County Ground, Leicester | Results |
| 15 Jul 1980 | Zone D | Glamorgan Under-25s v Gloucestershire Under-25s | Pontarddulais Park, Pontarddulais | Results |
| 15 Jul 1980 | Zone C | Kent Under-25s v Hampshire Under-25s | Spitfire Ground, St Lawrence, Canterbury | Results |
| 15 Jul 1980 | Zone A | Lancashire Under-25s v Yorkshire Under-25s | The CDM Windows Bentgate Cricket Ground, Haslingden | Results |
| 21 Jul 1980 | Zone D | Gloucestershire Under-25s v Worcestershire Under-25s | Seat Unique Stadium, Bristol | Results |
| 21 Jul 1980 | Zone B | Northamptonshire Under-25s v Middlesex Under-25s | County Ground, Northampton | Results |
| 21 Jul 1980 | Zone C | Surrey Under-25s v Sussex Under-25s | The Ridge, Purley | Results |
| 21 Jul 1980 | Zone D | Warwickshire Under-25s v Glamorgan Under-25s | Edgbaston, Birmingham | Results |
| 22 Jul 1980 | Zone C | Hampshire Under-25s v Sussex Under-25s | County Ground, Southampton | Results |
| 22 Jul 1980 | Zone D | Worcestershire Under-25s v Glamorgan Under-25s | Visit Worcestershire New Road, Worcester | Results |
| 28 Jul 1980 | Zone B | Essex Under-25s v Leicestershire Under-25s | The Cloud County Ground, Chelmsford | Results |
| 28 Jul 1980 | Zone C | Sussex Under-25s v Surrey Under-25s | Cricket Field Road, Horsham | Results |
| 29 Jul 1980 | Zone B | Essex Under-25s v Middlesex Under-25s | Hoffman's Sports and Social Club Ground, Chelmsford | Results |
| 01 Aug 1980 | Zone B | Northamptonshire Under-25s v Essex Under-25s | County Ground, Northampton | Results |
| 04 Aug 1980 | Zone C | Surrey Under-25s v Hampshire Under-25s | The Kia Oval, Kennington | Results |
| 08 Aug 1980 | Zone B | Essex Under-25s v Northamptonshire Under-25s | Harlow Sportcentre, Harlow | Results |
| 17 Aug 1980 | Semi-Final | Sussex Under-25s v Middlesex Under-25s | New County Ground, Hove | Results |
| 17 Aug 1980 | Semi-Final | Warwickshire Under-25s v Yorkshire Under-25s | Edgbaston, Birmingham | Results |
| 31 Aug 1980 | Final | Warwickshire Under-25s v Sussex Under-25s | Edgbaston, Birmingham | Results |
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