| 10 Jul 2022 | First Round | Herefordshire Under-18s v Cornwall Under-18s | Orlham Lane, Ledbury | Results |
| 10 Jul 2022 | First Round | Oxfordshire Under-18s v Isle of Wight Under-18s | Vicarage Hill, East Challow | Results |
| 10 Jul 2022 | First Round | Dorset Under-18s v Hampshire Under-18s | Hamworthy Recreation Cricket Club Ground, Wimborne | Results |
| 10 Jul 2022 | First Round | Somerset Under-18s v Wiltshire Under-18s | Taunton Vale Sports Club Ground, Taunton | Results |
| 11 Jul 2022 | First Round | Hertfordshire Under-18s v Suffolk Under-18s | Ditchmore Lane, Stevenage | Results |
| 11 Jul 2022 | First Round | Bedfordshire Under-18s v Cambridgeshire Under-18s | Southill Park, Southill | Results |
| 11 Jul 2022 | First Round | Buckinghamshire Under-18s v Berkshire Under-18s | Ostlers Lane, Stony Stratford | Results |
| 17 Jul 2022 | Second Round | Cornwall Under-18s v Oxfordshire Under-18s | Boscawen Park, Truro | Results |
| 17 Jul 2022 | Second Round | Hampshire Under-18s v Somerset Under-18s | Havant Park, Havant | Results |
| 22 Jul 2022 | Second Round | Suffolk Under-18s v Bedfordshire Under-18s | not known | Results |
| 17 Jul 2022 | Second Round | Norfolk Under-18s v Berkshire Under-18s | Walcis Park, Great Witchingham | Results |
| 21 Jul 2022 | Second Round | Lincolnshire Under-18s v Staffordshire Under-18s | Gorse Lane, Grantham | Results |
| 17 Jul 2022 | Second Round | Leicestershire Under-18s v Shropshire Under-18s | Leicester Ivanhoe Cricket Club Ground, Kirby Muxloe | Results |
| 07 Jul 2022 | Second Round | Northumberland Under-18s v Scotland Under-18s | The Wicket, Alnmouth | Results |
| 25 Jul 2022 | Second Round | Cheshire Under-18s v Cumbria Under-18s | Moss Farm Recreation Centre, Northwich | Results |
| 07 Aug 2022 | Quarter-Final | Cornwall Under-18s v Somerset Under-18s | Roskear, Camborne | Results |
| 07 Aug 2022 | Quarter-Final | Suffolk Under-18s v Berkshire Under-18s | not known | Results |
| 07 Aug 2022 | Quarter-Final | Staffordshire Under-18s v Leicestershire Under-18s | Jack Threlfall Memorial Ground, Fordhouses | Results |
| 12 Aug 2022 | Quarter-Final | Scotland Under-18s v Cheshire Under-18s | not known | Results |
| 21 Aug 2022 | Semi-Final | Somerset Under-18s v Berkshire Under-18s | Wells Cathedral School Ground, Wells | Results |
| 23 Aug 2022 | Semi-Final | Staffordshire Under-18s v Cheshire Under-18s | Faldo Close, Branston | Results |
| 04 Sep 2022 | Final | Berkshire Under-18s v Staffordshire Under-18s | Kibworth Cricket Club Ground, Kibworth | Results |
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