| 22 May 2022 | First Round | Aldershot v Waltham | Guildford Road, Aldershot | Results |
| 22 May 2022 | First Round | Banstead v Paragon | Recreation Ground, Banstead | Results |
| 05 Jun 2022 | First Round | Bromley v Roffey | Plaistow Lane, Bromley | Results |
| 22 May 2022 | First Round | Eastcote v Broxbourne | Haydon Hall, Eastcote | Results |
| 22 May 2022 | First Round | Egham v Wraysbury | Vicarage Road, Egham | Results |
| 22 May 2022 | First Round | Finchley v Abbots Langley | Arden Field, Finchley | Results |
| 22 May 2022 | First Round | Harefield v Hornsey | Woods Cricket Ground, Harefield | Results |
| 22 May 2022 | First Round | Harrow Town v Totteridge Millhillians | Harrow Town Sports Club Ground, Harrow | Results |
| 22 May 2022 | First Round | Hertford v Ealing | Balls Park, Hertford | Results |
| 22 May 2022 | First Round | Hornchurch v Dartford | Harrow Lodge Park, Hornchurch | Results |
| 22 May 2022 | First Round | Minster (Sheppey) v Spencer | Gilbert Hall, Minster | Results |
| 22 May 2022 | First Round | Oxted and Limpsfield v Sunbury | Master Park, Oxted | Results |
| 22 May 2022 | First Round | Wanstead and Snaresbrook v Enfield | Overton Drive, Wanstead | Results |
| 22 May 2022 | First Round | Watford Town v South Hampstead | Woodside, Watford | Results |
| 22 May 2022 | First Round | Wimbledon v Blackheath | Church Road, Wimbledon | Results |
| 22 May 2022 | First Round | Winchmore Hill v Shenfield | The Paulin Ground, Winchmore Hill | Results |
| 12 Jun 2022 | Second Round | Acton v Winchmore Hill | Manor Park Grounds, Acton | Results |
| 12 Jun 2022 | Second Round | Brentwood v Stanmore | Old County Ground, Brentwood | Results |
| 12 Jun 2022 | Second Round | Camberley v Reigate Priory | Upper Verran Road, Camberley | Results |
| 12 Jun 2022 | Second Round | Hutton v Ealing | The Polo Field Ground, Hutton | Results |
| 12 Jun 2022 | Second Round | Indian Gymkhana v East Molesey | Thornbury Avenue, Osterley | Results |
| 12 Jun 2022 | Second Round | Harefield v Ickenham | Woods Cricket Ground, Harefield | Results |
| 12 Jun 2022 | Second Round | Blackheath v Sandwich Town | The Rectory Field, Blackheath | Results |
| 12 Jun 2022 | Second Round | Egham v Oxted and Limpsfield | Vicarage Road, Egham | Results |
| 12 Jun 2022 | Second Round | Eastcote v Hoddesdon | Haydon Hall, Eastcote | Results |
| 12 Jun 2022 | Second Round | Spencer v Banstead | Spencer Cricket Club Ground, Earlsfield | Results |
| 19 Jun 2022 | Second Round | Finchley v Harrow Town | Arden Field, Finchley | Results |
| 12 Jun 2022 | Second Round | Old Hamptonians v Waltham | Dean Road, Hampton | Results |
| 12 Jun 2022 | Second Round | Sawston and Babraham v Wanstead and Snaresbrook | Spicer's Sports Ground, Sawston | Results |
| 19 Jun 2022 | Second Round | Three Bridges v Roffey | Three Bridges Road, Three Bridges | Results |
| 12 Jun 2022 | Second Round | Tunbridge Wells v Hornchurch | The Nevill Ground, Tunbridge Wells | Results |
| 12 Jun 2022 | Second Round | Walton-on-Thames v South Hampstead | Ashley Park, Walton-on-Thames | Results |
| 03 Jul 2022 | Third Round | Spencer v Old Hamptonians | Spencer Cricket Club Ground, Earlsfield | Results |
| 10 Jul 2022 | Third Round | Camberley v Egham | Upper Verran Road, Camberley | Results |
| 03 Jul 2022 | Third Round | Wanstead and Snaresbrook v Sandwich Town | Overton Drive, Wanstead | Results |
| 03 Jul 2022 | Third Round | Hoddesdon v Brentwood | Lowfield, Hoddesdon | Results |
| 03 Jul 2022 | Third Round | Roffey v Harefield | Crawley Road, Horsham | Results |
| 03 Jul 2022 | Third Round | Walton-on-Thames v Acton | Ashley Park, Walton-on-Thames | Results |
| 03 Jul 2022 | Third Round | Hutton v Finchley | The Polo Field Ground, Hutton | Results |
| 03 Jul 2022 | Third Round | East Molesey v Tunbridge Wells | Memorial Cricket Ground, East Molesey | Results |
| 24 Jul 2022 | Quarter-Final | Acton v Sandwich Town | Manor Park Grounds, Acton | Results |
| 31 Jul 2022 | Quarter-Final | Brentwood v East Molesey | Old County Ground, Brentwood | Results |
| 24 Jul 2022 | Quarter-Final | Spencer v Roffey | Spencer Cricket Club Ground, Earlsfield | Results |
| 24 Jul 2022 | Quarter-Final | Finchley v Camberley | Dean Road, Hampton | Results |
| 14 Aug 2022 | Semi-Final | Camberley v Sandwich Town | Upper Verran Road, Camberley | Results |
| 14 Aug 2022 | Semi-Final | Brentwood v Spencer | Old County Ground, Brentwood | Results |
| 17 Sep 2022 | Final | Brentwood v Camberley | Woods Cricket Ground, Harefield | Results |
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