| 23 Apr 2022 | First Round | Benfleet v Horndon-on-the-Hill | Woodside Park, Thundersley | Results |
| 23 Apr 2022 | First Round | Buckhurst Hill v Harlow Town | Roding Lane, Buckhurst Hill | Results |
| 23 Apr 2022 | First Round | Chingford v Belhus | Forest Side, Chingford | Results |
| 23 Apr 2022 | First Round | Colchester and East Essex v Epping | Castle Park Cricket Ground, Colchester | Results |
| 23 Apr 2022 | First Round | Gidea Park and Romford v Oakfield Parkonians | Gidea Park Sports Ground, Romford | Results |
| 23 Apr 2022 | First Round | Harold Wood v Orsett and Thurrock | Harold Wood Park, Harold Wood | Results |
| 23 Apr 2022 | First Round | Hornchurch v Fives and Heronians | Harrow Lodge Park, Hornchurch | Results |
| 23 Apr 2022 | First Round | Hutton v Shenfield | The Polo Field Ground, Hutton | Results |
| 23 Apr 2022 | First Round | Ilford v Leigh-on-Sea | Valentine's Park, Ilford | Results |
| 23 Apr 2022 | First Round | Old Brentwoods v Old Southendian and Southchurch | Ashwells Road, Brentwood | Results |
| 23 Apr 2022 | First Round | Upminster v Loughton | Upminster Park, Upminster | Results |
| 23 Apr 2022 | First Round | Westcliff-on-Sea v Billericay | Chalkwell Park, Westcliff-on-Sea | Results |
| 23 Apr 2022 | First Round | Wickford v Chelmsford | Dick Patmore Memorial Ground, Wickford | Results |
| 23 Apr 2022 | First Round | Woodford Wells v Hadleigh and Thundersley | Monkham Lane, Woodford Wells | Results |
| 30 Apr 2022 | Second Round | Brentwood v Wanstead and Snaresbrook | Old County Ground, Brentwood | Results |
| 30 Apr 2022 | Second Round | Chelmsford v Epping | Chelmer Park, Chelmsford | Results |
| 30 Apr 2022 | Second Round | Hadleigh and Thundersley v Billericay | John H Burrows Recreation Ground, Hadleigh | Results |
| 30 Apr 2022 | Second Round | Harold Wood v Oakfield Parkonians | Harold Wood Park, Harold Wood | Results |
| 30 Apr 2022 | Second Round | Buckhurst Hill v Ilford | Roding Lane, Buckhurst Hill | Results |
| 30 Apr 2022 | Second Round | Upminster v Shenfield | Upminster Park, Upminster | Results |
| 30 Apr 2022 | Second Round | Chingford v Horndon-on-the-Hill | Forest Side, Chingford | Results |
| 30 Apr 2022 | Second Round | Hornchurch v Old Southendian and Southchurch | Harrow Lodge Park, Hornchurch | Results |
| 26 Jun 2022 | Quarter-Final | Billericay v Chingford | The Toby Howe Cricket Ground, Billericay | Results |
| 10 Jul 2022 | Quarter-Final | Hornchurch v Harold Wood | Harrow Lodge Park, Hornchurch | Results |
| 24 Jul 2022 | Quarter-Final | Buckhurst Hill v Chelmsford | Roding Lane, Buckhurst Hill | Results |
| 24 Jul 2022 | Quarter-Final | Upminster v Brentwood | Upminster Park, Upminster | Results |
| 14 Aug 2022 | Semi-Final | Chingford v Harold Wood | Forest Side, Chingford | Results |
| 28 Aug 2022 | Semi-Final | Chelmsford v Brentwood | Chelmer Park, Chelmsford | Results |
| 10 Sep 2022 | Final | Chelmsford v Chingford | Overton Drive, Wanstead | Results |
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