| 22 Apr 1905 | | Stand v Horwich | Hamilton Road, Whitefield | Results |
| 22 Apr 1905 | | Swinton v Prestwich | Barton Road, Swinton | Results |
| 29 Apr 1905 | | Clifton v Stand | Manchester Road, Clifton | Results |
| 29 Apr 1905 | | Horwich v Thornham | The Recreation Ground, Horwich | Results |
| 29 Apr 1905 | | Swinton v South East Manchester | Barton Road, Swinton | Results |
| 29 Apr 1905 | | Unsworth v Eccles | Parr Lane, Unsworth | Results |
| 06 May 1905 | | Eccles v Clifton | GP Codie's Ground, Eccles | Results |
| 06 May 1905 | | Rhodes v Horwich | Rhodes | Results |
| 06 May 1905 | | Thornham v Swinton | Rochdale Road, Slattocks | Results |
| 06 May 1905 | | Unsworth v South East Manchester | Parr Lane, Unsworth | Results |
| 13 May 1905 | | Horwich v Prestwich | The Recreation Ground, Horwich | Results |
| 13 May 1905 | | Stand v Eccles | Hamilton Road, Whitefield | Results |
| 13 May 1905 | | South East Manchester v Clifton | Manchester | Results |
| 13 May 1905 | | Thornham v Rhodes | Rochdale Road, Slattocks | Results |
| 20 May 1905 | | Clifton v Thornham | Manchester Road, Clifton | Results |
| 20 May 1905 | | Eccles v Rhodes | GP Codie's Ground, Eccles | Results |
| 20 May 1905 | | Horwich v Unsworth | The Recreation Ground, Horwich | Results |
| 20 May 1905 | | Prestwich v South East Manchester | The Heys, Prestwich | Results |
| 20 May 1905 | | Swinton v Stand | Barton Road, Swinton | Results |
| 27 May 1905 | | Eccles v Horwich | GP Codie's Ground, Eccles | Results |
| 27 May 1905 | | South East Manchester v Rhodes | Manchester | Results |
| 27 May 1905 | | Stand v Clifton | Hamilton Road, Whitefield | Results |
| 27 May 1905 | | Thornham v Prestwich | Rochdale Road, Slattocks | Results |
| 27 May 1905 | | Unsworth v Swinton | Parr Lane, Unsworth | Results |
| 03 Jun 1905 | | Clifton v Unsworth | Manchester Road, Clifton | Results |
| 03 Jun 1905 | | Prestwich v Eccles | The Heys, Prestwich | Results |
| 03 Jun 1905 | | Rhodes v Swinton | Rhodes | Results |
| 03 Jun 1905 | | South East Manchester v Horwich | Manchester | Results |
| 03 Jun 1905 | | Thornham v Stand | Rochdale Road, Slattocks | Results |
| 10 Jun 1905 | | Eccles v Thornham | GP Codie's Ground, Eccles | Results |
| 10 Jun 1905 | | Rhodes v South East Manchester | Rhodes | Results |
| 10 Jun 1905 | | Stand v Prestwich | Hamilton Road, Whitefield | Results |
| 10 Jun 1905 | | Swinton v Clifton | Barton Road, Swinton | Results |
| 14 Jun 1905 | | Swinton v Eccles | Barton Road, Swinton | Results |
| 15 Jun 1905 | | Prestwich v Unsworth | The Heys, Prestwich | Results |
| 17 Jun 1905 | | Prestwich v Rhodes | The Heys, Prestwich | Results |
| 24 Jun 1905 | | Clifton v Prestwich | Manchester Road, Clifton | Results |
| 24 Jun 1905 | | Horwich v Swinton | The Recreation Ground, Horwich | Results |
| 24 Jun 1905 | | Rhodes v Eccles | Rhodes | Results |
| 24 Jun 1905 | | Stand v Thornham | Hamilton Road, Whitefield | Results |
| 24 Jun 1905 | | South East Manchester v Unsworth | Manchester | Results |
| 01 Jul 1905 | | Eccles v South East Manchester | GP Codie's Ground, Eccles | Results |
| 01 Jul 1905 | | Prestwich v Horwich | The Heys, Prestwich | Results |
| 01 Jul 1905 | | Rhodes v Clifton | Rhodes | Results |
| 01 Jul 1905 | | Swinton v Thornham | Barton Road, Swinton | Results |
| 01 Jul 1905 | | Unsworth v Stand | Parr Lane, Unsworth | Results |
| 08 Jul 1905 | | Clifton v Eccles | Manchester Road, Clifton | Results |
| 08 Jul 1905 | | South East Manchester v Swinton | Manchester | Results |
| 08 Jul 1905 | | Thornham v Horwich | Rochdale Road, Slattocks | Results |
| 08 Jul 1905 | | Unsworth v Rhodes | Parr Lane, Unsworth | Results |
| 15 Jul 1905 | | Swinton v Horwich | Barton Road, Swinton | Results |
| 15 Jul 1905 | | Stand v South East Manchester | Hamilton Road, Whitefield | Results |
| 15 Jul 1905 | | Thornham v Unsworth | Rochdale Road, Slattocks | Results |
| 22 Jul 1905 | | Eccles v Stand | GP Codie's Ground, Eccles | Results |
| 22 Jul 1905 | | Horwich v Rhodes | The Recreation Ground, Horwich | Results |
| 22 Jul 1905 | | South East Manchester v Prestwich | Manchester | Results |
| 22 Jul 1905 | | Swinton v Unsworth | Barton Road, Swinton | Results |
| 22 Jul 1905 | | Thornham v Clifton | Rochdale Road, Slattocks | Results |
| 29 Jul 1905 | | Clifton v Swinton | Manchester Road, Clifton | Results |
| 29 Jul 1905 | | Horwich v Eccles | The Recreation Ground, Horwich | Results |
| 29 Jul 1905 | | Prestwich v Stand | The Heys, Prestwich | Results |
| 29 Jul 1905 | | Rhodes v Unsworth | Rhodes | Results |
| 29 Jul 1905 | | South East Manchester v Thornham | Manchester | Results |
| 05 Aug 1905 | | Horwich v South East Manchester | The Recreation Ground, Horwich | Results |
| 05 Aug 1905 | | Prestwich v Thornham | The Heys, Prestwich | Results |
| 05 Aug 1905 | | Stand v Rhodes | Hamilton Road, Whitefield | Results |
| 05 Aug 1905 | | Unsworth v Clifton | Parr Lane, Unsworth | Results |
| 07 Aug 1905 | | Eccles v Prestwich | GP Codie's Ground, Eccles | Results |
| 12 Aug 1905 | | Eccles v Swinton | GP Codie's Ground, Eccles | Results |
| 12 Aug 1905 | | Prestwich v Clifton | The Heys, Prestwich | Results |
| 12 Aug 1905 | | Rhodes v Thornham | Rhodes | Results |
| 12 Aug 1905 | | Stand v Unsworth | Hamilton Road, Whitefield | Results |
| 19 Aug 1905 | | Clifton v Horwich | Manchester Road, Clifton | Results |
| 19 Aug 1905 | | Swinton v Rhodes | Barton Road, Swinton | Results |
| 19 Aug 1905 | | South East Manchester v Stand | Manchester | Results |
| 19 Aug 1905 | | Unsworth v Prestwich | Parr Lane, Unsworth | Results |
| 26 Aug 1905 | | Clifton v South East Manchester | Manchester Road, Clifton | Results |
| 26 Aug 1905 | | Rhodes v Prestwich | Rhodes | Results |
| 26 Aug 1905 | | Stand v Swinton | Hamilton Road, Whitefield | Results |
| 26 Aug 1905 | | Thornham v Eccles | Rochdale Road, Slattocks | Results |
| 26 Aug 1905 | | Unsworth v Horwich | Parr Lane, Unsworth | Results |
| 02 Sep 1905 | | Horwich v Clifton | The Recreation Ground, Horwich | Results |
| 02 Sep 1905 | | Prestwich v Swinton | The Heys, Prestwich | Results |
| 02 Sep 1905 | | Rhodes v Stand | Rhodes | Results |
| 02 Sep 1905 | | South East Manchester v Eccles | Manchester | Results |
| 02 Sep 1905 | | Unsworth v Thornham | Parr Lane, Unsworth | Results |
| 09 Sep 1905 | | Clifton v Rhodes | Manchester Road, Clifton | Results |
| 09 Sep 1905 | | Eccles v Unsworth | GP Codie's Ground, Eccles | Results |
| 09 Sep 1905 | | Horwich v Stand | The Recreation Ground, Horwich | Results |
| 09 Sep 1905 | | Thornham v South East Manchester | Rochdale Road, Slattocks | Results |
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