| 21 Apr 1900 | | Chancery Lane v Beswick | Manchester | Results |
| 21 Apr 1900 | | Cornbrook v East Gorton | Cornbrook | Results |
| 21 Apr 1900 | | Lancashire Hill v Kirkmanshulme | Manchester | Results |
| 21 Apr 1900 | | North-East Manchester v Hurst | Manchester | Results |
| 28 Apr 1900 | | East Gorton v Chancery Lane | East Gorton | Results |
| 28 Apr 1900 | | Hurst v Lancashire Hill | Wokingham Road, Hurst | Results |
| 28 Apr 1900 | | Beswick v Hightown Congregational | Beswick | Results |
| 28 Apr 1900 | | Kirkmanshulme v Cornbrook | Kirkmanshulme | Results |
| 05 May 1900 | | Kirkmanshulme v Hurst | Kirkmanshulme | Results |
| 05 May 1900 | | Cornbrook v Chancery Lane | Cornbrook | Results |
| 05 May 1900 | | North-East Manchester v Beswick | Manchester | Results |
| 05 May 1900 | | Hightown Congregational v East Gorton | Hightown, Manchester | Results |
| 12 May 1900 | | Beswick v Lancashire Hill | Beswick | Results |
| 12 May 1900 | | East Gorton v North-East Manchester | East Gorton | Results |
| 12 May 1900 | | Chancery Lane v Hightown Congregational | Manchester | Results |
| 12 May 1900 | | Hurst v Cornbrook | Wokingham Road, Hurst | Results |
| 19 May 1900 | | Cornbrook v Hightown Congregational | Cornbrook | Results |
| 19 May 1900 | | Kirkmanshulme v Beswick | Kirkmanshulme | Results |
| 19 May 1900 | | North-East Manchester v Chancery Lane | Manchester | Results |
| 19 May 1900 | | Lancashire Hill v East Gorton | Manchester | Results |
| 26 May 1900 | | Chancery Lane v Lancashire Hill | Manchester | Results |
| 26 May 1900 | | East Gorton v Kirkmanshulme | East Gorton | Results |
| 26 May 1900 | | Hightown Congregational v North-East Manchester | Hightown, Manchester | Results |
| 26 May 1900 | | Beswick v Hurst | Beswick | Results |
| 02 Jun 1900 | | Kirkmanshulme v Chancery Lane | Kirkmanshulme | Results |
| 02 Jun 1900 | | Cornbrook v North-East Manchester | Cornbrook | Results |
| 02 Jun 1900 | | Lancashire Hill v Pilsley Colliery | Manchester | Results |
| 02 Jun 1900 | | Hurst v East Gorton | Wokingham Road, Hurst | Results |
| 16 Jun 1900 | | North-East Manchester v Lancashire Hill | Manchester | Results |
| 16 Jun 1900 | | Chancery Lane v Hurst | Manchester | Results |
| 16 Jun 1900 | | Beswick v Cornbrook | Beswick | Results |
| 16 Jun 1900 | | Hightown Congregational v Kirkmanshulme | Hightown, Manchester | Results |
| 23 Jun 1900 | | East Gorton v Beswick | East Gorton | Results |
| 23 Jun 1900 | | Cornbrook v Lancashire Hill | Cornbrook | Results |
| 23 Jun 1900 | | Hurst v Pilsley Colliery | Wokingham Road, Hurst | Results |
| 23 Jun 1900 | | Kirkmanshulme v North-East Manchester | Kirkmanshulme | Results |
| 30 Jun 1900 | | Hurst v North-East Manchester | Wokingham Road, Hurst | Results |
| 30 Jun 1900 | | Kirkmanshulme v Lancashire Hill | Kirkmanshulme | Results |
| 30 Jun 1900 | | Beswick v Chancery Lane | Beswick | Results |
| 30 Jun 1900 | | East Gorton v Cornbrook | East Gorton | Results |
| 07 Jul 1900 | | Hightown Congregational v Beswick | Hightown, Manchester | Results |
| 07 Jul 1900 | | Chancery Lane v East Gorton | Manchester | Results |
| 07 Jul 1900 | | Lancashire Hill v Hurst | Manchester | Results |
| 07 Jul 1900 | | Cornbrook v Kirkmanshulme | Cornbrook | Results |
| 14 Jul 1900 | | Beswick v North-East Manchester | Beswick | Results |
| 14 Jul 1900 | | East Gorton v Hightown Congregational | East Gorton | Results |
| 14 Jul 1900 | | Chancery Lane v Cornbrook | Manchester | Results |
| 14 Jul 1900 | | Hurst v Kirkmanshulme | Wokingham Road, Hurst | Results |
| 21 Jul 1900 | | Cornbrook v Hurst | Cornbrook | Results |
| 21 Jul 1900 | | Hightown Congregational v Chancery Lane | Hightown, Manchester | Results |
| 21 Jul 1900 | | North-East Manchester v East Gorton | Manchester | Results |
| 21 Jul 1900 | | Lancashire Hill v Beswick | Manchester | Results |
| 28 Jul 1900 | | East Gorton v Lancashire Hill | East Gorton | Results |
| 28 Jul 1900 | | Chancery Lane v North-East Manchester | Manchester | Results |
| 28 Jul 1900 | | Beswick v Kirkmanshulme | Beswick | Results |
| 28 Jul 1900 | | Hightown Congregational v Cornbrook | Hightown, Manchester | Results |
| 04 Aug 1900 | | Lancashire Hill v Chancery Lane | Manchester | Results |
| 04 Aug 1900 | | Kirkmanshulme v East Gorton | Kirkmanshulme | Results |
| 04 Aug 1900 | | North-East Manchester v Hightown Congregational | Manchester | Results |
| 04 Aug 1900 | | Hurst v Beswick | Wokingham Road, Hurst | Results |
| 11 Aug 1900 | | Hightown Congregational v Lancashire Hill | Hightown, Manchester | Results |
| 11 Aug 1900 | | Hurst v East Gorton | Wokingham Road, Hurst | Results |
| 11 Aug 1900 | | North-East Manchester v Cornbrook | Manchester | Results |
| 11 Aug 1900 | | Chancery Lane v Kirkmanshulme | Manchester | Results |
| 18 Aug 1900 | | Hurst v Chancery Lane | Wokingham Road, Hurst | Results |
| 18 Aug 1900 | | Lancashire Hill v North-East Manchester | Manchester | Results |
| 18 Aug 1900 | | Cornbrook v Beswick | Cornbrook | Results |
| 18 Aug 1900 | | Kirkmanshulme v Hightown Congregational | Kirkmanshulme | Results |
| 25 Aug 1900 | | North-East Manchester v Kirkmanshulme | Manchester | Results |
| 25 Aug 1900 | | Hightown Congregational v Hurst | Hightown, Manchester | Results |
| 25 Aug 1900 | | Beswick v East Gorton | Beswick | Results |
| 25 Aug 1900 | | Lancashire Hill v Cornbrook | Manchester | Results |
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