| 21 May 1980 | Preliminary Round | Three Counties Cricket League v Sussex Championship | not known | Results |
| 04 Jun 1980 | First Round | Morrant Essex Cricket League v Essex Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Middlesex Cricketers League v Cambridgeshire Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Middlesex Cricket League v Essex County Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Hertfordshire Cricket League v North Kent Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Chilterns Cricket League v Middlesex County Cricket League | not known | Results |
| 04 Jun 1980 | First Round | West Middlesex Cricket League v Berkshire County Cricket League | not known | Results |
| 04 Jun 1980 | First Round | 1975 Cricket League v Thames Valley Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Trinity Cricket League v Cherwell Cricket League | Christ Church Ground, Oxford | Results |
| 04 Jun 1980 | First Round | Surrey County Cricket League v East Kent Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Mid-Kent Cricket League v Wandsworth Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Kent Metropolitan Cricket League v Kent Cricket League | RACS Sports Ground, New Eltham | Results |
| 04 Jun 1980 | First Round | South Thames Cricket League v Central London Cricket League | Crescent Farm, Sidcup | Results |
| 04 Jun 1980 | First Round | Surrey Cricket League v Southern Cricket League | Westfield | Results |
| 04 Jun 1980 | First Round | Surrey Championship v Three Counties Cricket League | Beddington Park, Wallington | Results |
| 04 Jun 1980 | First Round | Surrey Cricketers League v Wey Valley Cricket League | not known | Results |
| 04 Jun 1980 | First Round | Sussex Cricket League v Thameside Cricket League | not known | Results |
| 25 Jun 1980 | Second Round | Essex Cricket League v Essex County Cricket League | not known | Results |
| 25 Jun 1980 | Second Round | Hertfordshire Cricket League v Cherwell Cricket League | not known | Results |
| 25 Jun 1980 | Second Round | Middlesex Cricketers League v Middlesex County Cricket League | not known | Results |
| 25 Jun 1980 | Second Round | Thames Valley Cricket League v not known | not known | Results |
| 25 Jun 1980 | Second Round | East Kent Cricket League v South Thames Cricket League | The Grove, Hythe | Results |
| 25 Jun 1980 | Second Round | Sussex Cricket League v Surrey Championship | Three Bridges Road, Three Bridges | Results |
| 25 Jun 1980 | Second Round | Mid-Kent Cricket League v Southern Cricket League | Wouldham Road, Borstal | Results |
| 25 Jun 1980 | Second Round | Kent Metropolitan Cricket League v Surrey Cricketers League | Metrogas Amateur Sports Association Ground, Greenwich | Results |
| 16 Jul 1980 | Third Round | Thames Valley Cricket League v Cherwell Cricket League | not known | Results |
| 16 Jul 1980 | Third Round | Essex Cricket League v Middlesex Cricketers League | not known | Results |
| 16 Jul 1980 | Third Round | South Thames Cricket League v Southern Cricket League | Commercial Union Assurance Company Ground, Beckenham | Results |
| 16 Jul 1980 | Third Round | Surrey Championship v Kent Metropolitan Cricket League | Cambridge Avenue, New Malden | Results |
| 06 Aug 1980 | Semi-Final | Southern Cricket League v Surrey Championship | Ridding Field, Winchester | Results |
| 06 Aug 1980 | Semi-Final | Thames Valley Cricket League v Essex Cricket League | London Road, High Wycombe | Results |
| 10 Sep 1980 | Final | Surrey Championship v Thames Valley Cricket League | Spitfire Ground, St Lawrence, Canterbury | Results |
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