| 17 Apr 2010 | | Adlington v Golborne | Huyton Road, Adlington | Results |
| 17 Apr 2010 | | Blackrod v Walshaw | Vicarage Road, Blackrod | Results |
| 17 Apr 2010 | | Daisy Hill v Atherton | St James Street, Daisy Hill | Results |
| 17 Apr 2010 | | Darcy Lever v Edgworth | The Levers, Darcy Lever | Results |
| 17 Apr 2010 | | Elton v Spring View | Leigh Lane, Elton | Results |
| 17 Apr 2010 | | Flixton v Little Hulton | Lawrence Road, Flixton | Results |
| 17 Apr 2010 | | Standish v Astley and Tyldesley | Green Lane, Standish | Results |
| 24 Apr 2010 | | Astley and Tyldesley v Flixton | Meanley Road, Astley | Results |
| 24 Apr 2010 | | Atherton v Elton | Higham Park, Atherton | Results |
| 24 Apr 2010 | | Edgworth v Standish | Barlow Memorial Ground, Edgworth | Results |
| 24 Apr 2010 | | Golborne v Daisy Hill | Simpson Fields, Lowton | Results |
| 24 Apr 2010 | | Little Hulton v Adlington | The Old Vicarage, Little Hulton | Results |
| 24 Apr 2010 | | Spring View v Blackrod | Dower House Farm, Spring View | Results |
| 24 Apr 2010 | | Walshaw v Darcy Lever | Sycamore Road, Tottington | Results |
| 01 May 2010 | | Adlington v Daisy Hill | Huyton Road, Adlington | Results |
| 01 May 2010 | | Blackrod v Atherton | Vicarage Road, Blackrod | Results |
| 01 May 2010 | | Darcy Lever v Spring View | The Levers, Darcy Lever | Results |
| 01 May 2010 | | Elton v Golborne | Leigh Lane, Elton | Results |
| 01 May 2010 | | Flixton v Edgworth | Lawrence Road, Flixton | Results |
| 01 May 2010 | | Little Hulton v Astley and Tyldesley | The Old Vicarage, Little Hulton | Results |
| 01 May 2010 | | Standish v Walshaw | Green Lane, Standish | Results |
| 08 May 2010 | | Astley and Tyldesley v Adlington | Meanley Road, Astley | Results |
| 08 May 2010 | | Atherton v Darcy Lever | Higham Park, Atherton | Results |
| 08 May 2010 | | Daisy Hill v Elton | St James Street, Daisy Hill | Results |
| 08 May 2010 | | Edgworth v Little Hulton | Barlow Memorial Ground, Edgworth | Results |
| 08 May 2010 | | Golborne v Blackrod | Simpson Fields, Lowton | Results |
| 08 May 2010 | | Spring View v Standish | Dower House Farm, Spring View | Results |
| 08 May 2010 | | Walshaw v Flixton | Sycamore Road, Tottington | Results |
| 15 May 2010 | | Adlington v Elton | Huyton Road, Adlington | Results |
| 15 May 2010 | | Astley and Tyldesley v Edgworth | Meanley Road, Astley | Results |
| 15 May 2010 | | Blackrod v Daisy Hill | Vicarage Road, Blackrod | Results |
| 15 May 2010 | | Darcy Lever v Golborne | The Levers, Darcy Lever | Results |
| 15 May 2010 | | Flixton v Spring View | Lawrence Road, Flixton | Results |
| 15 May 2010 | | Little Hulton v Walshaw | The Old Vicarage, Little Hulton | Results |
| 15 May 2010 | | Standish v Atherton | Green Lane, Standish | Results |
| 22 May 2010 | | Atherton v Flixton | Higham Park, Atherton | Results |
| 22 May 2010 | | Daisy Hill v Darcy Lever | St James Street, Daisy Hill | Results |
| 22 May 2010 | | Edgworth v Adlington | Barlow Memorial Ground, Edgworth | Results |
| 22 May 2010 | | Elton v Blackrod | Leigh Lane, Elton | Results |
| 22 May 2010 | | Golborne v Standish | Simpson Fields, Lowton | Results |
| 22 May 2010 | | Spring View v Little Hulton | Dower House Farm, Spring View | Results |
| 22 May 2010 | | Walshaw v Astley and Tyldesley | Sycamore Road, Tottington | Results |
| 29 May 2010 | | Adlington v Blackrod | Huyton Road, Adlington | Results |
| 29 May 2010 | | Astley and Tyldesley v Spring View | Meanley Road, Astley | Results |
| 29 May 2010 | | Darcy Lever v Elton | The Levers, Darcy Lever | Results |
| 29 May 2010 | | Edgworth v Walshaw | Barlow Memorial Ground, Edgworth | Results |
| 29 May 2010 | | Flixton v Golborne | Lawrence Road, Flixton | Results |
| 29 May 2010 | | Little Hulton v Atherton | The Old Vicarage, Little Hulton | Results |
| 29 May 2010 | | Standish v Daisy Hill | Green Lane, Standish | Results |
| 05 Jun 2010 | | Atherton v Astley and Tyldesley | Higham Park, Atherton | Results |
| 05 Jun 2010 | | Blackrod v Darcy Lever | Vicarage Road, Blackrod | Results |
| 05 Jun 2010 | | Daisy Hill v Flixton | St James Street, Daisy Hill | Results |
| 05 Jun 2010 | | Elton v Standish | Leigh Lane, Elton | Results |
| 05 Jun 2010 | | Golborne v Little Hulton | Simpson Fields, Lowton | Results |
| 05 Jun 2010 | | Spring View v Edgworth | Dower House Farm, Spring View | Results |
| 05 Jun 2010 | | Walshaw v Adlington | Sycamore Road, Tottington | Results |
| 12 Jun 2010 | | Adlington v Darcy Lever | Huyton Road, Adlington | Results |
| 12 Jun 2010 | | Astley and Tyldesley v Golborne | Meanley Road, Astley | Results |
| 12 Jun 2010 | | Edgworth v Atherton | Barlow Memorial Ground, Edgworth | Results |
| 12 Jun 2010 | | Flixton v Elton | Lawrence Road, Flixton | Results |
| 12 Jun 2010 | | Little Hulton v Daisy Hill | The Old Vicarage, Little Hulton | Results |
| 12 Jun 2010 | | Standish v Blackrod | Green Lane, Standish | Results |
| 12 Jun 2010 | | Walshaw v Spring View | Sycamore Road, Tottington | Results |
| 19 Jun 2010 | | Atherton v Walshaw | Higham Park, Atherton | Results |
| 19 Jun 2010 | | Blackrod v Flixton | Vicarage Road, Blackrod | Results |
| 19 Jun 2010 | | Daisy Hill v Astley and Tyldesley | St James Street, Daisy Hill | Results |
| 19 Jun 2010 | | Darcy Lever v Standish | The Levers, Darcy Lever | Results |
| 19 Jun 2010 | | Elton v Little Hulton | Leigh Lane, Elton | Results |
| 19 Jun 2010 | | Golborne v Edgworth | Simpson Fields, Lowton | Results |
| 19 Jun 2010 | | Spring View v Adlington | Dower House Farm, Spring View | Results |
| 26 Jun 2010 | | Adlington v Standish | Huyton Road, Adlington | Results |
| 26 Jun 2010 | | Astley and Tyldesley v Elton | Meanley Road, Astley | Results |
| 26 Jun 2010 | | Edgworth v Daisy Hill | Barlow Memorial Ground, Edgworth | Results |
| 26 Jun 2010 | | Flixton v Darcy Lever | Lawrence Road, Flixton | Results |
| 26 Jun 2010 | | Little Hulton v Blackrod | The Old Vicarage, Little Hulton | Results |
| 26 Jun 2010 | | Spring View v Atherton | Dower House Farm, Spring View | Results |
| 26 Jun 2010 | | Walshaw v Golborne | Sycamore Road, Tottington | Results |
| 03 Jul 2010 | | Adlington v Atherton | Huyton Road, Adlington | Results |
| 03 Jul 2010 | | Blackrod v Astley and Tyldesley | Vicarage Road, Blackrod | Results |
| 03 Jul 2010 | | Daisy Hill v Walshaw | St James Street, Daisy Hill | Results |
| 03 Jul 2010 | | Darcy Lever v Little Hulton | The Levers, Darcy Lever | Results |
| 03 Jul 2010 | | Elton v Edgworth | Leigh Lane, Elton | Results |
| 03 Jul 2010 | | Golborne v Spring View | Simpson Fields, Lowton | Results |
| 03 Jul 2010 | | Standish v Flixton | Green Lane, Standish | Results |
| 04 Jul 2010 | | Astley and Tyldesley v Darcy Lever | Meanley Road, Astley | Results |
| 04 Jul 2010 | | Atherton v Golborne | Higham Park, Atherton | Results |
| 04 Jul 2010 | | Edgworth v Blackrod | Barlow Memorial Ground, Edgworth | Results |
| 04 Jul 2010 | | Flixton v Adlington | Lawrence Road, Flixton | Results |
| 04 Jul 2010 | | Little Hulton v Standish | The Old Vicarage, Little Hulton | Results |
| 04 Jul 2010 | | Spring View v Daisy Hill | Dower House Farm, Spring View | Results |
| 04 Jul 2010 | | Walshaw v Elton | Sycamore Road, Tottington | Results |
| 10 Jul 2010 | | Astley and Tyldesley v Standish | Meanley Road, Astley | Results |
| 10 Jul 2010 | | Atherton v Daisy Hill | Higham Park, Atherton | Results |
| 10 Jul 2010 | | Edgworth v Darcy Lever | Barlow Memorial Ground, Edgworth | Results |
| 10 Jul 2010 | | Golborne v Adlington | Simpson Fields, Lowton | Results |
| 10 Jul 2010 | | Little Hulton v Flixton | The Old Vicarage, Little Hulton | Results |
| 10 Jul 2010 | | Spring View v Elton | Dower House Farm, Spring View | Results |
| 10 Jul 2010 | | Walshaw v Blackrod | Sycamore Road, Tottington | Results |
| 17 Jul 2010 | | Adlington v Little Hulton | Huyton Road, Adlington | Results |
| 17 Jul 2010 | | Blackrod v Spring View | Vicarage Road, Blackrod | Results |
| 17 Jul 2010 | | Daisy Hill v Golborne | St James Street, Daisy Hill | Results |
| 17 Jul 2010 | | Darcy Lever v Walshaw | The Levers, Darcy Lever | Results |
| 17 Jul 2010 | | Elton v Atherton | Leigh Lane, Elton | Results |
| 17 Jul 2010 | | Flixton v Astley and Tyldesley | Lawrence Road, Flixton | Results |
| 17 Jul 2010 | | Standish v Edgworth | Green Lane, Standish | Results |
| 24 Jul 2010 | | Astley and Tyldesley v Little Hulton | Meanley Road, Astley | Results |
| 24 Jul 2010 | | Atherton v Blackrod | Higham Park, Atherton | Results |
| 24 Jul 2010 | | Daisy Hill v Adlington | St James Street, Daisy Hill | Results |
| 24 Jul 2010 | | Edgworth v Flixton | Barlow Memorial Ground, Edgworth | Results |
| 24 Jul 2010 | | Golborne v Elton | Simpson Fields, Lowton | Results |
| 24 Jul 2010 | | Spring View v Darcy Lever | Dower House Farm, Spring View | Results |
| 24 Jul 2010 | | Walshaw v Standish | Sycamore Road, Tottington | Results |
| 31 Jul 2010 | | Adlington v Astley and Tyldesley | Huyton Road, Adlington | Results |
| 31 Jul 2010 | | Blackrod v Golborne | Vicarage Road, Blackrod | Results |
| 31 Jul 2010 | | Darcy Lever v Atherton | The Levers, Darcy Lever | Results |
| 31 Jul 2010 | | Elton v Daisy Hill | Leigh Lane, Elton | Results |
| 31 Jul 2010 | | Flixton v Walshaw | Lawrence Road, Flixton | Results |
| 31 Jul 2010 | | Little Hulton v Edgworth | The Old Vicarage, Little Hulton | Results |
| 31 Jul 2010 | | Standish v Spring View | Green Lane, Standish | Results |
| 01 Aug 2010 | | Atherton v Standish | Higham Park, Atherton | Results |
| 01 Aug 2010 | | Daisy Hill v Blackrod | St James Street, Daisy Hill | Results |
| 01 Aug 2010 | | Edgworth v Astley and Tyldesley | Barlow Memorial Ground, Edgworth | Results |
| 01 Aug 2010 | | Elton v Adlington | Leigh Lane, Elton | Results |
| 01 Aug 2010 | | Golborne v Darcy Lever | Simpson Fields, Lowton | Results |
| 01 Aug 2010 | | Spring View v Flixton | Dower House Farm, Spring View | Results |
| 01 Aug 2010 | | Walshaw v Little Hulton | Sycamore Road, Tottington | Results |
| 07 Aug 2010 | | Adlington v Edgworth | Huyton Road, Adlington | Results |
| 07 Aug 2010 | | Astley and Tyldesley v Walshaw | Meanley Road, Astley | Results |
| 07 Aug 2010 | | Blackrod v Elton | Vicarage Road, Blackrod | Results |
| 07 Aug 2010 | | Darcy Lever v Daisy Hill | The Levers, Darcy Lever | Results |
| 07 Aug 2010 | | Flixton v Atherton | Lawrence Road, Flixton | Results |
| 07 Aug 2010 | | Little Hulton v Spring View | The Old Vicarage, Little Hulton | Results |
| 07 Aug 2010 | | Standish v Golborne | Green Lane, Standish | Results |
| 14 Aug 2010 | | Atherton v Little Hulton | Higham Park, Atherton | Results |
| 14 Aug 2010 | | Blackrod v Adlington | Vicarage Road, Blackrod | Results |
| 14 Aug 2010 | | Daisy Hill v Standish | St James Street, Daisy Hill | Results |
| 14 Aug 2010 | | Elton v Darcy Lever | Leigh Lane, Elton | Results |
| 14 Aug 2010 | | Golborne v Flixton | Simpson Fields, Lowton | Results |
| 14 Aug 2010 | | Spring View v Astley and Tyldesley | Dower House Farm, Spring View | Results |
| 14 Aug 2010 | | Walshaw v Edgworth | Sycamore Road, Tottington | Results |
| 21 Aug 2010 | | Little Hulton v Golborne | The Old Vicarage, Little Hulton | Results |
| 21 Aug 2010 | | Adlington v Walshaw | Huyton Road, Adlington | Results |
| 21 Aug 2010 | | Astley and Tyldesley v Atherton | Meanley Road, Astley | Results |
| 21 Aug 2010 | | Darcy Lever v Blackrod | The Levers, Darcy Lever | Results |
| 21 Aug 2010 | | Edgworth v Spring View | Barlow Memorial Ground, Edgworth | Results |
| 21 Aug 2010 | | Flixton v Daisy Hill | Lawrence Road, Flixton | Results |
| 21 Aug 2010 | | Standish v Elton | Green Lane, Standish | Results |
| 28 Aug 2010 | | Atherton v Edgworth | Higham Park, Atherton | Results |
| 28 Aug 2010 | | Blackrod v Standish | Vicarage Road, Blackrod | Results |
| 28 Aug 2010 | | Daisy Hill v Little Hulton | St James Street, Daisy Hill | Results |
| 28 Aug 2010 | | Darcy Lever v Adlington | The Levers, Darcy Lever | Results |
| 28 Aug 2010 | | Elton v Flixton | Leigh Lane, Elton | Results |
| 28 Aug 2010 | | Golborne v Astley and Tyldesley | Simpson Fields, Lowton | Results |
| 28 Aug 2010 | | Spring View v Walshaw | Dower House Farm, Spring View | Results |
| 04 Sep 2010 | | Astley and Tyldesley v Daisy Hill | Meanley Road, Astley | Results |
| 04 Sep 2010 | | Adlington v Spring View | Huyton Road, Adlington | Results |
| 04 Sep 2010 | | Edgworth v Golborne | Barlow Memorial Ground, Edgworth | Results |
| 04 Sep 2010 | | Flixton v Blackrod | Lawrence Road, Flixton | Results |
| 04 Sep 2010 | | Little Hulton v Elton | The Old Vicarage, Little Hulton | Results |
| 04 Sep 2010 | | Standish v Darcy Lever | Green Lane, Standish | Results |
| 04 Sep 2010 | | Walshaw v Atherton | Sycamore Road, Tottington | Results |
| 05 Sep 2010 | | Daisy Hill v Edgworth | St James Street, Daisy Hill | Results |
| 05 Sep 2010 | | Atherton v Spring View | Higham Park, Atherton | Results |
| 05 Sep 2010 | | Blackrod v Little Hulton | Vicarage Road, Blackrod | Results |
| 05 Sep 2010 | | Darcy Lever v Flixton | The Levers, Darcy Lever | Results |
| 05 Sep 2010 | | Elton v Astley and Tyldesley | Leigh Lane, Elton | Results |
| 05 Sep 2010 | | Golborne v Walshaw | Simpson Fields, Lowton | Results |
| 05 Sep 2010 | | Standish v Adlington | Green Lane, Standish | Results |
| 11 Sep 2010 | | Astley and Tyldesley v Blackrod | Meanley Road, Astley | Results |
| 11 Sep 2010 | | Atherton v Adlington | Higham Park, Atherton | Results |
| 11 Sep 2010 | | Edgworth v Elton | Barlow Memorial Ground, Edgworth | Results |
| 11 Sep 2010 | | Flixton v Standish | Lawrence Road, Flixton | Results |
| 11 Sep 2010 | | Little Hulton v Darcy Lever | The Old Vicarage, Little Hulton | Results |
| 11 Sep 2010 | | Spring View v Golborne | Dower House Farm, Spring View | Results |
| 11 Sep 2010 | | Walshaw v Daisy Hill | Sycamore Road, Tottington | Results |
| 18 Sep 2010 | | Adlington v Flixton | Huyton Road, Adlington | Results |
| 18 Sep 2010 | | Blackrod v Edgworth | Vicarage Road, Blackrod | Results |
| 18 Sep 2010 | | Daisy Hill v Spring View | St James Street, Daisy Hill | Results |
| 18 Sep 2010 | | Darcy Lever v Astley and Tyldesley | The Levers, Darcy Lever | Results |
| 18 Sep 2010 | | Elton v Walshaw | Leigh Lane, Elton | Results |
| 18 Sep 2010 | | Golborne v Atherton | Simpson Fields, Lowton | Results |
| 18 Sep 2010 | | Standish v Little Hulton | Green Lane, Standish | Results |
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