| 22 May 2010 | | Hindley St Peters v Winton | St Peters Recreation Ground, Hindley | Results |
| 22 May 2010 | | Newton Heath v Bolton Indians | Greaves Field, Newton Heath | Results |
| 22 May 2010 | | Swinton Moorside v Bury | Moorside Park, Swinton | Results |
| 22 May 2010 | | Whalley Range v Euxton | Kingsbrook Road, Whalley Range | Results |
| 22 May 2010 | | Wythenshawe v Stretford | Longley Lane, Northenden | Results |
| 29 May 2010 | | Bolton Indians v Hindley St Peters | Hacken Lane, Darcy Lever | Results |
| 29 May 2010 | | Bury v Wythenshawe | Radcliffe Road, Bury | Results |
| 29 May 2010 | | Euxton v Newton Heath | Balshaw Park, Euxton | Results |
| 29 May 2010 | | Stretford v Whalley Range | The Boundary, Stretford | Results |
| 29 May 2010 | | Winton v Swinton Moorside | Alder Forest Avenue, Winton | Results |
| 05 Jun 2010 | | Hindley St Peters v Newton Heath | St Peters Recreation Ground, Hindley | Results |
| 05 Jun 2010 | | Stretford v Euxton | The Boundary, Stretford | Results |
| 05 Jun 2010 | | Swinton Moorside v Bolton Indians | Moorside Park, Swinton | Results |
| 05 Jun 2010 | | Whalley Range v Bury | Kingsbrook Road, Whalley Range | Results |
| 05 Jun 2010 | | Wythenshawe v Winton | Longley Lane, Northenden | Results |
| 12 Jun 2010 | | Bolton Indians v Wythenshawe | Hacken Lane, Darcy Lever | Results |
| 12 Jun 2010 | | Bury v Stretford | Radcliffe Road, Bury | Results |
| 12 Jun 2010 | | Euxton v Hindley St Peters | Balshaw Park, Euxton | Results |
| 12 Jun 2010 | | Newton Heath v Swinton Moorside | Greaves Field, Newton Heath | Results |
| 12 Jun 2010 | | Winton v Whalley Range | Alder Forest Avenue, Winton | Results |
| 19 Jun 2010 | | Bury v Euxton | Radcliffe Road, Bury | Results |
| 19 Jun 2010 | | Stretford v Winton | The Boundary, Stretford | Results |
| 19 Jun 2010 | | Swinton Moorside v Hindley St Peters | Moorside Park, Swinton | Results |
| 19 Jun 2010 | | Whalley Range v Bolton Indians | Kingsbrook Road, Whalley Range | Results |
| 19 Jun 2010 | | Wythenshawe v Newton Heath | Longley Lane, Northenden | Results |
| 26 Jun 2010 | | Bolton Indians v Stretford | Hacken Lane, Darcy Lever | Results |
| 26 Jun 2010 | | Euxton v Swinton Moorside | Balshaw Park, Euxton | Results |
| 26 Jun 2010 | | Hindley St Peters v Wythenshawe | St Peters Recreation Ground, Hindley | Results |
| 26 Jun 2010 | | Newton Heath v Whalley Range | Greaves Field, Newton Heath | Results |
| 26 Jun 2010 | | Winton v Bury | Alder Forest Avenue, Winton | Results |
| 03 Jul 2010 | | Bury v Bolton Indians | Radcliffe Road, Bury | Results |
| 03 Jul 2010 | | Stretford v Newton Heath | The Boundary, Stretford | Results |
| 03 Jul 2010 | | Whalley Range v Hindley St Peters | Kingsbrook Road, Whalley Range | Results |
| 03 Jul 2010 | | Winton v Euxton | Alder Forest Avenue, Winton | Results |
| 03 Jul 2010 | | Wythenshawe v Swinton Moorside | Longley Lane, Northenden | Results |
| 10 Jul 2010 | | Bolton Indians v Winton | Hacken Lane, Darcy Lever | Results |
| 10 Jul 2010 | | Hindley St Peters v Stretford | St Peters Recreation Ground, Hindley | Results |
| 10 Jul 2010 | | Newton Heath v Bury | Greaves Field, Newton Heath | Results |
| 10 Jul 2010 | | Swinton Moorside v Whalley Range | Moorside Park, Swinton | Results |
| 10 Jul 2010 | | Wythenshawe v Euxton | Longley Lane, Northenden | Results |
| 17 Jul 2010 | | Bury v Hindley St Peters | Radcliffe Road, Bury | Results |
| 17 Jul 2010 | | Euxton v Bolton Indians | Balshaw Park, Euxton | Results |
| 17 Jul 2010 | | Stretford v Swinton Moorside | The Boundary, Stretford | Results |
| 17 Jul 2010 | | Whalley Range v Wythenshawe | Kingsbrook Road, Whalley Range | Results |
| 17 Jul 2010 | | Winton v Newton Heath | Alder Forest Avenue, Winton | Results |
| 24 Jul 2010 | | Bolton Indians v Newton Heath | Hacken Lane, Darcy Lever | Results |
| 24 Jul 2010 | | Bury v Swinton Moorside | Radcliffe Road, Bury | Results |
| 24 Jul 2010 | | Euxton v Whalley Range | Balshaw Park, Euxton | Results |
| 24 Jul 2010 | | Stretford v Wythenshawe | The Boundary, Stretford | Results |
| 24 Jul 2010 | | Winton v Hindley St Peters | Alder Forest Avenue, Winton | Results |
| 31 Jul 2010 | | Hindley St Peters v Bolton Indians | St Peters Recreation Ground, Hindley | Results |
| 31 Jul 2010 | | Newton Heath v Euxton | Greaves Field, Newton Heath | Results |
| 31 Jul 2010 | | Swinton Moorside v Winton | Moorside Park, Swinton | Results |
| 31 Jul 2010 | | Whalley Range v Stretford | Kingsbrook Road, Whalley Range | Results |
| 31 Jul 2010 | | Wythenshawe v Bury | Longley Lane, Northenden | Results |
| 07 Aug 2010 | | Bolton Indians v Swinton Moorside | Hacken Lane, Darcy Lever | Results |
| 07 Aug 2010 | | Bury v Whalley Range | Radcliffe Road, Bury | Results |
| 07 Aug 2010 | | Euxton v Stretford | Balshaw Park, Euxton | Results |
| 07 Aug 2010 | | Newton Heath v Hindley St Peters | Greaves Field, Newton Heath | Results |
| 07 Aug 2010 | | Winton v Wythenshawe | Alder Forest Avenue, Winton | Results |
| 14 Aug 2010 | | Hindley St Peters v Euxton | St Peters Recreation Ground, Hindley | Results |
| 14 Aug 2010 | | Stretford v Bury | The Boundary, Stretford | Results |
| 14 Aug 2010 | | Swinton Moorside v Newton Heath | Moorside Park, Swinton | Results |
| 14 Aug 2010 | | Whalley Range v Winton | Kingsbrook Road, Whalley Range | Results |
| 14 Aug 2010 | | Wythenshawe v Bolton Indians | Longley Lane, Northenden | Results |
| 21 Aug 2010 | | Bolton Indians v Whalley Range | Hacken Lane, Darcy Lever | Results |
| 21 Aug 2010 | | Euxton v Bury | Balshaw Park, Euxton | Results |
| 21 Aug 2010 | | Hindley St Peters v Swinton Moorside | St Peters Recreation Ground, Hindley | Results |
| 21 Aug 2010 | | Newton Heath v Wythenshawe | Greaves Field, Newton Heath | Results |
| 21 Aug 2010 | | Winton v Stretford | Alder Forest Avenue, Winton | Results |
| 28 Aug 2010 | | Bury v Winton | Radcliffe Road, Bury | Results |
| 28 Aug 2010 | | Stretford v Bolton Indians | The Boundary, Stretford | Results |
| 28 Aug 2010 | | Swinton Moorside v Euxton | Moorside Park, Swinton | Results |
| 28 Aug 2010 | | Whalley Range v Newton Heath | Kingsbrook Road, Whalley Range | Results |
| 28 Aug 2010 | | Wythenshawe v Hindley St Peters | Longley Lane, Northenden | Results |
| 04 Sep 2010 | | Bolton Indians v Bury | Hacken Lane, Darcy Lever | Results |
| 04 Sep 2010 | | Euxton v Winton | Balshaw Park, Euxton | Results |
| 04 Sep 2010 | | Hindley St Peters v Whalley Range | St Peters Recreation Ground, Hindley | Results |
| 04 Sep 2010 | | Newton Heath v Stretford | Greaves Field, Newton Heath | Results |
| 04 Sep 2010 | | Wythenshawe v Swinton Moorside | Longley Lane, Northenden | Results |
| 11 Sep 2010 | | Bury v Newton Heath | Radcliffe Road, Bury | Results |
| 11 Sep 2010 | | Euxton v Wythenshawe | Balshaw Park, Euxton | Results |
| 11 Sep 2010 | | Stretford v Hindley St Peters | The Boundary, Stretford | Results |
| 11 Sep 2010 | | Whalley Range v Swinton Moorside | Kingsbrook Road, Whalley Range | Results |
| 11 Sep 2010 | | Winton v Bolton Indians | Alder Forest Avenue, Winton | Results |
| 18 Sep 2010 | | Bolton Indians v Euxton | Hacken Lane, Darcy Lever | Results |
| 18 Sep 2010 | | Hindley St Peters v Bury | St Peters Recreation Ground, Hindley | Results |
| 18 Sep 2010 | | Newton Heath v Winton | Greaves Field, Newton Heath | Results |
| 18 Sep 2010 | | Swinton Moorside v Stretford | Moorside Park, Swinton | Results |
| 18 Sep 2010 | | Wythenshawe v Whalley Range | Longley Lane, Northenden | Results |
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