| 21 Apr 2001 | | Alder v Prescot and Odyssey | Alder Road, Liverpool | Results |
| 21 Apr 2001 | | Liverpool Manweb v Wavertree | Thingwall Road, Liverpool | Results |
| 21 Apr 2001 | | Prestatyn v Ainsdale | Beach Close, Prestatyn | Results |
| 21 Apr 2001 | | Rainhill v Aigburth | Rainhill Recreation Ground, Rainhill | Results |
| 21 Apr 2001 | | Sutton v Cheshire Lines | New Street, Sutton | Results |
| 28 Apr 2001 | | Aigburth v Alder | Southwood Road, Liverpool | Results |
| 28 Apr 2001 | | Birkenhead St Mary's v Liverpool Manweb | Ashville Road, Birkenhead Park | Results |
| 28 Apr 2001 | | Cheshire Lines v Rainhill | Southmead Road, Allerton | Results |
| 28 Apr 2001 | | Prescot and Odyssey v Prestatyn | Burrows Lane, Prescot | Results |
| 28 Apr 2001 | | Wavertree v Sutton | Sandown Lane, Wavertree | Results |
| 05 May 2001 | | Alder v Cheshire Lines | Alder Road, Liverpool | Results |
| 05 May 2001 | | Liverpool Manweb v Ainsdale | Thingwall Road, Liverpool | Results |
| 05 May 2001 | | Prestatyn v Aigburth | Beach Close, Prestatyn | Results |
| 05 May 2001 | | Sutton v Rainhill | New Street, Sutton | Results |
| 05 May 2001 | | Wavertree v Birkenhead St Mary's | Sandown Lane, Wavertree | Results |
| 12 May 2001 | | Ainsdale v Wavertree | Liverpool Road, Ainsdale | Results |
| 12 May 2001 | | Birkenhead St Mary's v Sutton | Ashville Road, Birkenhead Park | Results |
| 12 May 2001 | | Cheshire Lines v Prestatyn | Southmead Road, Allerton | Results |
| 12 May 2001 | | Prescot and Odyssey v Liverpool Manweb | Burrows Lane, Prescot | Results |
| 12 May 2001 | | Rainhill v Alder | Rainhill Recreation Ground, Rainhill | Results |
| 19 May 2001 | | Birkenhead St Mary's v Ainsdale | Ashville Road, Birkenhead Park | Results |
| 19 May 2001 | | Liverpool Manweb v Aigburth | Thingwall Road, Liverpool | Results |
| 19 May 2001 | | Prestatyn v Rainhill | Beach Close, Prestatyn | Results |
| 19 May 2001 | | Sutton v Alder | New Street, Sutton | Results |
| 19 May 2001 | | Wavertree v Prescot and Odyssey | Sandown Lane, Wavertree | Results |
| 26 May 2001 | | Aigburth v Wavertree | Southwood Road, Liverpool | Results |
| 26 May 2001 | | Ainsdale v Sutton | Liverpool Road, Ainsdale | Results |
| 26 May 2001 | | Alder v Prestatyn | Alder Road, Liverpool | Results |
| 26 May 2001 | | Cheshire Lines v Liverpool Manweb | Southmead Road, Allerton | Results |
| 26 May 2001 | | Prescot and Odyssey v Birkenhead St Mary's | Burrows Lane, Prescot | Results |
| 02 Jun 2001 | | Ainsdale v Prescot and Odyssey | Liverpool Road, Ainsdale | Results |
| 02 Jun 2001 | | Birkenhead St Mary's v Aigburth | Ashville Road, Birkenhead Park | Results |
| 02 Jun 2001 | | Liverpool Manweb v Rainhill | Thingwall Road, Liverpool | Results |
| 02 Jun 2001 | | Sutton v Prestatyn | New Street, Sutton | Results |
| 02 Jun 2001 | | Wavertree v Cheshire Lines | Sandown Lane, Wavertree | Results |
| 09 Jun 2001 | | Aigburth v Ainsdale | Southwood Road, Liverpool | Results |
| 09 Jun 2001 | | Alder v Liverpool Manweb | Alder Road, Liverpool | Results |
| 09 Jun 2001 | | Cheshire Lines v Birkenhead St Mary's | Southmead Road, Allerton | Results |
| 09 Jun 2001 | | Prescot and Odyssey v Sutton | Burrows Lane, Prescot | Results |
| 09 Jun 2001 | | Rainhill v Wavertree | Rainhill Recreation Ground, Rainhill | Results |
| 16 Jun 2001 | | Birkenhead St Mary's v Rainhill | Ashville Road, Birkenhead Park | Results |
| 16 Jun 2001 | | Cheshire Lines v Ainsdale | Southmead Road, Allerton | Results |
| 16 Jun 2001 | | Liverpool Manweb v Prestatyn | Thingwall Road, Liverpool | Results |
| 16 Jun 2001 | | Prescot and Odyssey v Aigburth | Burrows Lane, Prescot | Results |
| 16 Jun 2001 | | Wavertree v Alder | Sandown Lane, Wavertree | Results |
| 23 Jun 2001 | | Aigburth v Sutton | Southwood Road, Liverpool | Results |
| 23 Jun 2001 | | Alder v Birkenhead St Mary's | Alder Road, Liverpool | Results |
| 23 Jun 2001 | | Cheshire Lines v Prescot and Odyssey | Southmead Road, Allerton | Results |
| 23 Jun 2001 | | Prestatyn v Wavertree | Beach Close, Prestatyn | Results |
| 23 Jun 2001 | | Rainhill v Ainsdale | Rainhill Recreation Ground, Rainhill | Results |
| 30 Jun 2001 | | Ainsdale v Alder | Liverpool Road, Ainsdale | Results |
| 30 Jun 2001 | | Birkenhead St Mary's v Prestatyn | Ashville Road, Birkenhead Park | Results |
| 30 Jun 2001 | | Cheshire Lines v Aigburth | Southmead Road, Allerton | Results |
| 30 Jun 2001 | | Liverpool Manweb v Sutton | Thingwall Road, Liverpool | Results |
| 30 Jun 2001 | | Prescot and Odyssey v Rainhill | Burrows Lane, Prescot | Results |
| 07 Jul 2001 | | Aigburth v Rainhill | Southwood Road, Liverpool | Results |
| 07 Jul 2001 | | Ainsdale v Prestatyn | Liverpool Road, Ainsdale | Results |
| 07 Jul 2001 | | Cheshire Lines v Sutton | Southmead Road, Allerton | Results |
| 07 Jul 2001 | | Prescot and Odyssey v Alder | Burrows Lane, Prescot | Results |
| 07 Jul 2001 | | Wavertree v Liverpool Manweb | Sandown Lane, Wavertree | Results |
| 14 Jul 2001 | | Alder v Aigburth | Alder Road, Liverpool | Results |
| 14 Jul 2001 | | Liverpool Manweb v Birkenhead St Mary's | Thingwall Road, Liverpool | Results |
| 14 Jul 2001 | | Prestatyn v Prescot and Odyssey | Beach Close, Prestatyn | Results |
| 14 Jul 2001 | | Rainhill v Cheshire Lines | Rainhill Recreation Ground, Rainhill | Results |
| 14 Jul 2001 | | Sutton v Wavertree | New Street, Sutton | Results |
| 21 Jul 2001 | | Aigburth v Prestatyn | Southwood Road, Liverpool | Results |
| 21 Jul 2001 | | Ainsdale v Liverpool Manweb | Liverpool Road, Ainsdale | Results |
| 21 Jul 2001 | | Birkenhead St Mary's v Wavertree | Ashville Road, Birkenhead Park | Results |
| 21 Jul 2001 | | Cheshire Lines v Alder | Southmead Road, Allerton | Results |
| 21 Jul 2001 | | Rainhill v Sutton | Rainhill Recreation Ground, Rainhill | Results |
| 28 Jul 2001 | | Alder v Rainhill | Alder Road, Liverpool | Results |
| 28 Jul 2001 | | Liverpool Manweb v Prescot and Odyssey | Thingwall Road, Liverpool | Results |
| 28 Jul 2001 | | Prestatyn v Cheshire Lines | Beach Close, Prestatyn | Results |
| 28 Jul 2001 | | Sutton v Birkenhead St Mary's | New Street, Sutton | Results |
| 28 Jul 2001 | | Wavertree v Ainsdale | Sandown Lane, Wavertree | Results |
| 04 Aug 2001 | | Aigburth v Liverpool Manweb | Southwood Road, Liverpool | Results |
| 04 Aug 2001 | | Ainsdale v Birkenhead St Mary's | Liverpool Road, Ainsdale | Results |
| 04 Aug 2001 | | Alder v Sutton | Alder Road, Liverpool | Results |
| 04 Aug 2001 | | Prescot and Odyssey v Wavertree | Burrows Lane, Prescot | Results |
| 04 Aug 2001 | | Rainhill v Prestatyn | Rainhill Recreation Ground, Rainhill | Results |
| 11 Aug 2001 | | Birkenhead St Mary's v Prescot and Odyssey | Ashville Road, Birkenhead Park | Results |
| 11 Aug 2001 | | Liverpool Manweb v Cheshire Lines | Thingwall Road, Liverpool | Results |
| 11 Aug 2001 | | Prestatyn v Alder | Beach Close, Prestatyn | Results |
| 11 Aug 2001 | | Sutton v Ainsdale | New Street, Sutton | Results |
| 11 Aug 2001 | | Wavertree v Aigburth | Sandown Lane, Wavertree | Results |
| 18 Aug 2001 | | Aigburth v Birkenhead St Mary's | Southwood Road, Liverpool | Results |
| 18 Aug 2001 | | Cheshire Lines v Wavertree | Southmead Road, Allerton | Results |
| 18 Aug 2001 | | Prescot and Odyssey v Ainsdale | Burrows Lane, Prescot | Results |
| 18 Aug 2001 | | Prestatyn v Sutton | Beach Close, Prestatyn | Results |
| 18 Aug 2001 | | Rainhill v Liverpool Manweb | Rainhill Recreation Ground, Rainhill | Results |
| 25 Aug 2001 | | Ainsdale v Aigburth | Liverpool Road, Ainsdale | Results |
| 25 Aug 2001 | | Birkenhead St Mary's v Cheshire Lines | Ashville Road, Birkenhead Park | Results |
| 25 Aug 2001 | | Liverpool Manweb v Alder | Thingwall Road, Liverpool | Results |
| 25 Aug 2001 | | Sutton v Prescot and Odyssey | New Street, Sutton | Results |
| 25 Aug 2001 | | Wavertree v Rainhill | Sandown Lane, Wavertree | Results |
| 01 Sep 2001 | | Aigburth v Prescot and Odyssey | Southwood Road, Liverpool | Results |
| 01 Sep 2001 | | Ainsdale v Cheshire Lines | Liverpool Road, Ainsdale | Results |
| 01 Sep 2001 | | Alder v Wavertree | Alder Road, Liverpool | Results |
| 01 Sep 2001 | | Prestatyn v Liverpool Manweb | Beach Close, Prestatyn | Results |
| 01 Sep 2001 | | Rainhill v Birkenhead St Mary's | Rainhill Recreation Ground, Rainhill | Results |
| 08 Sep 2001 | | Ainsdale v Rainhill | Liverpool Road, Ainsdale | Results |
| 08 Sep 2001 | | Birkenhead St Mary's v Alder | Ashville Road, Birkenhead Park | Results |
| 08 Sep 2001 | | Prescot and Odyssey v Cheshire Lines | Burrows Lane, Prescot | Results |
| 08 Sep 2001 | | Sutton v Aigburth | New Street, Sutton | Results |
| 08 Sep 2001 | | Wavertree v Prestatyn | Sandown Lane, Wavertree | Results |
| 15 Sep 2001 | | Aigburth v Cheshire Lines | Southwood Road, Liverpool | Results |
| 15 Sep 2001 | | Alder v Ainsdale | Alder Road, Liverpool | Results |
| 15 Sep 2001 | | Prestatyn v Birkenhead St Mary's | Beach Close, Prestatyn | Results |
| 15 Sep 2001 | | Rainhill v Prescot and Odyssey | Rainhill Recreation Ground, Rainhill | Results |
| 15 Sep 2001 | | Sutton v Liverpool Manweb | New Street, Sutton | Results |
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