| 13 May 2012 | Preliminary Round | Great Eccleston Second XI v Gregson Lane | Hall Lane, Great Eccleston | Results |
| 13 May 2012 | Preliminary Round | Kirkham and Wesham v Fylde Second XI | Woodlands Avenue, Kirkham | Results |
| 13 May 2012 | Preliminary Round | Longridge Second XI v BAC-EE Preston Second XI | George Newsham Memorial Cricket Ground, Longridge | Results |
| 13 May 2012 | Preliminary Round | New Longton Second XI v Norcross Second XI | Chapel Lane, New Longton | Results |
| 13 May 2012 | Preliminary Round | Vernon Carus Second XI v South Shore Second XI | Factory Lane, Penwortham | Results |
| 13 May 2012 | Preliminary Round | Whittle-le-Woods v Grimsargh | Kem Mill Lane, Whittle-le-Woods | Results |
| 13 May 2012 | Preliminary Round | Charnock Richard v Walton-le-Dale | Mossie Close, Charnock Richard | Results |
| 20 May 2012 | Preliminary Round | Garstang Second XI v Whittingham and Goosnargh Second XI | Riverside Sports Ground, Garstang | Results |
| 10 Jun 2012 | First Round | Whittingham and Goosnargh Second XI v Thornton Cleveleys Second XI | Guild Park, Whittingham | Results |
| 10 Jun 2012 | First Round | Mawdesley v Fulwood and Broughton Second XI | The Rectory Field, Mawdesley | Results |
| 10 Jun 2012 | First Round | Great Eccleston Second XI v Wrea Green | Hall Lane, Great Eccleston | Results |
| 10 Jun 2012 | First Round | Kirkham and Wesham v Vernon Carus Second XI | Woodlands Avenue, Kirkham | Results |
| 10 Jun 2012 | First Round | New Longton Second XI v White Coppice Second XI | Chapel Lane, New Longton | Results |
| 10 Jun 2012 | First Round | Grimsargh v Penwortham Second XI | The Green, Grimsargh | Results |
| 10 Jun 2012 | First Round | Caton v Longridge Second XI | Hornby Road, Caton | Results |
| 10 Jun 2012 | First Round | Withnell Fold v Walton-le-Dale | Withnell Fold, Higher Wheelton | Results |
| 01 Jul 2012 | Second Round | Fulwood and Broughton Second XI v Kirkham and Wesham | Highfield, Broughton | Results |
| 01 Jul 2012 | Second Round | Penwortham Second XI v Longridge Second XI | Middleforth Green, Penwortham | Results |
| 01 Jul 2012 | Second Round | Withnell Fold v Great Eccleston Second XI | Withnell Fold, Higher Wheelton | Results |
| 01 Jul 2012 | Second Round | New Longton Second XI v Whittingham and Goosnargh Second XI | Chapel Lane, New Longton | Results |
| 22 Jul 2012 | Semi-Final | Kirkham and Wesham v New Longton Second XI | Woodlands Avenue, Kirkham | Results |
| 22 Jul 2012 | Semi-Final | Longridge Second XI v Withnell Fold | George Newsham Memorial Cricket Ground, Longridge | Results |
| 12 Aug 2012 | Final | Kirkham and Wesham v Longridge Second XI | Boundary Meadow, Torrisholme | Results |
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