| 01 May 2010 | | Barking v Cosmopolitan Athletic | Mayesbrook Park, Barking | Results |
| 01 May 2010 | | Goresbrook v Ford Sports Club | May and Baker Annexe, Dagenham | Results |
| 01 May 2010 | | Hornchurch Athletic v Bow Green | Hylands Park, Hornchurch | Results |
| 01 May 2010 | | Leyton County v Thurrock | County Ground, Leyton | Results |
| 01 May 2010 | | May and Baker v Asian | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 08 May 2010 | | Asian v Goresbrook | Low Hall Sports Arena, Walthamstow | Results |
| 08 May 2010 | | Bow Green v Leyton County | West Ham Park, Stratford | Results |
| 08 May 2010 | | Cosmopolitan Athletic v May and Baker | Fairlop Oak Recreation Ground, Hainault | Results |
| 08 May 2010 | | Ford Sports Club v Hornchurch Athletic | Fords Sports Club Ground, Newbury Park | Results |
| 08 May 2010 | | Thurrock v Barking | King George Playing Field, Grays | Results |
| 15 May 2010 | | Barking v Asian | Mayesbrook Park, Barking | Results |
| 15 May 2010 | | Goresbrook v Bow Green | May and Baker Annexe, Dagenham | Results |
| 15 May 2010 | | Leyton County v Hornchurch Athletic | County Ground, Leyton | Results |
| 15 May 2010 | | May and Baker v Ford Sports Club | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 15 May 2010 | | Thurrock v Cosmopolitan Athletic | King George Playing Field, Grays | Results |
| 22 May 2010 | | Asian v Thurrock | Low Hall Sports Arena, Walthamstow | Results |
| 22 May 2010 | | Bow Green v May and Baker | West Ham Park, Stratford | Results |
| 22 May 2010 | | Cosmopolitan Athletic v Leyton County | Fairlop Oak Recreation Ground, Hainault | Results |
| 22 May 2010 | | Ford Sports Club v Barking | Fords Sports Club Ground, Newbury Park | Results |
| 22 May 2010 | | Hornchurch Athletic v Goresbrook | Hylands Park, Hornchurch | Results |
| 29 May 2010 | | Barking v Hornchurch Athletic | Mayesbrook Park, Barking | Results |
| 29 May 2010 | | Cosmopolitan Athletic v Ford Sports Club | Fairlop Oak Recreation Ground, Hainault | Results |
| 29 May 2010 | | Leyton County v Asian | County Ground, Leyton | Results |
| 29 May 2010 | | May and Baker v Goresbrook | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 29 May 2010 | | Thurrock v Bow Green | King George Playing Field, Grays | Results |
| 05 Jun 2010 | | Asian v Cosmopolitan Athletic | Low Hall Sports Arena, Walthamstow | Results |
| 05 Jun 2010 | | Bow Green v Barking | West Ham Park, Stratford | Results |
| 05 Jun 2010 | | Ford Sports Club v Thurrock | Fords Sports Club Ground, Newbury Park | Results |
| 05 Jun 2010 | | Goresbrook v Leyton County | May and Baker Annexe, Dagenham | Results |
| 05 Jun 2010 | | Hornchurch Athletic v May and Baker | Hylands Park, Hornchurch | Results |
| 12 Jun 2010 | | Barking v Leyton County | Mayesbrook Park, Barking | Results |
| 12 Jun 2010 | | Bow Green v Ford Sports Club | West Ham Park, Stratford | Results |
| 12 Jun 2010 | | Goresbrook v Cosmopolitan Athletic | May and Baker Annexe, Dagenham | Results |
| 12 Jun 2010 | | Hornchurch Athletic v Asian | Hylands Park, Hornchurch | Results |
| 12 Jun 2010 | | May and Baker v Thurrock | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 19 Jun 2010 | | Asian v Ford Sports Club | Low Hall Sports Arena, Walthamstow | Results |
| 19 Jun 2010 | | Barking v Goresbrook | Mayesbrook Park, Barking | Results |
| 19 Jun 2010 | | Cosmopolitan Athletic v Bow Green | Fairlop Oak Recreation Ground, Hainault | Results |
| 19 Jun 2010 | | Leyton County v May and Baker | County Ground, Leyton | Results |
| 19 Jun 2010 | | Thurrock v Hornchurch Athletic | King George Playing Field, Grays | Results |
| 26 Jun 2010 | | Bow Green v Asian | West Ham Park, Stratford | Results |
| 26 Jun 2010 | | Ford Sports Club v Leyton County | Fords Sports Club Ground, Newbury Park | Results |
| 26 Jun 2010 | | Goresbrook v Thurrock | May and Baker Annexe, Dagenham | Results |
| 26 Jun 2010 | | Hornchurch Athletic v Cosmopolitan Athletic | Hylands Park, Hornchurch | Results |
| 26 Jun 2010 | | May and Baker v Barking | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 03 Jul 2010 | | Asian v May and Baker | Low Hall Sports Arena, Walthamstow | Results |
| 03 Jul 2010 | | Bow Green v Hornchurch Athletic | West Ham Park, Stratford | Results |
| 03 Jul 2010 | | Cosmopolitan Athletic v Barking | Fairlop Oak Recreation Ground, Hainault | Results |
| 03 Jul 2010 | | Ford Sports Club v Goresbrook | Fords Sports Club Ground, Newbury Park | Results |
| 03 Jul 2010 | | Thurrock v Leyton County | King George Playing Field, Grays | Results |
| 10 Jul 2010 | | Barking v Thurrock | Mayesbrook Park, Barking | Results |
| 10 Jul 2010 | | Goresbrook v Asian | May and Baker Annexe, Dagenham | Results |
| 10 Jul 2010 | | Hornchurch Athletic v Ford Sports Club | Hylands Park, Hornchurch | Results |
| 10 Jul 2010 | | Leyton County v Bow Green | County Ground, Leyton | Results |
| 10 Jul 2010 | | May and Baker v Cosmopolitan Athletic | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 17 Jul 2010 | | Asian v Barking | Low Hall Sports Arena, Walthamstow | Results |
| 17 Jul 2010 | | Bow Green v Goresbrook | West Ham Park, Stratford | Results |
| 17 Jul 2010 | | Cosmopolitan Athletic v Thurrock | Fairlop Oak Recreation Ground, Hainault | Results |
| 17 Jul 2010 | | Ford Sports Club v May and Baker | Fords Sports Club Ground, Newbury Park | Results |
| 17 Jul 2010 | | Hornchurch Athletic v Leyton County | Hylands Park, Hornchurch | Results |
| 24 Jul 2010 | | Barking v Ford Sports Club | Mayesbrook Park, Barking | Results |
| 24 Jul 2010 | | Goresbrook v Hornchurch Athletic | May and Baker Annexe, Dagenham | Results |
| 24 Jul 2010 | | Leyton County v Cosmopolitan Athletic | County Ground, Leyton | Results |
| 24 Jul 2010 | | May and Baker v Bow Green | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 24 Jul 2010 | | Thurrock v Asian | King George Playing Field, Grays | Results |
| 31 Jul 2010 | | Asian v Leyton County | Low Hall Sports Arena, Walthamstow | Results |
| 31 Jul 2010 | | Bow Green v Thurrock | West Ham Park, Stratford | Results |
| 31 Jul 2010 | | Ford Sports Club v Cosmopolitan Athletic | Fords Sports Club Ground, Newbury Park | Results |
| 31 Jul 2010 | | Goresbrook v May and Baker | May and Baker Annexe, Dagenham | Results |
| 31 Jul 2010 | | Hornchurch Athletic v Barking | Hylands Park, Hornchurch | Results |
| 07 Aug 2010 | | Barking v Bow Green | Mayesbrook Park, Barking | Results |
| 07 Aug 2010 | | Cosmopolitan Athletic v Asian | Fairlop Oak Recreation Ground, Hainault | Results |
| 07 Aug 2010 | | Leyton County v Goresbrook | County Ground, Leyton | Results |
| 07 Aug 2010 | | May and Baker v Hornchurch Athletic | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 07 Aug 2010 | | Thurrock v Ford Sports Club | King George Playing Field, Grays | Results |
| 14 Aug 2010 | | Asian v Hornchurch Athletic | Low Hall Sports Arena, Walthamstow | Results |
| 14 Aug 2010 | | Cosmopolitan Athletic v Goresbrook | Fairlop Oak Recreation Ground, Hainault | Results |
| 14 Aug 2010 | | Ford Sports Club v Bow Green | Fords Sports Club Ground, Newbury Park | Results |
| 14 Aug 2010 | | Leyton County v Barking | County Ground, Leyton | Results |
| 14 Aug 2010 | | Thurrock v May and Baker | King George Playing Field, Grays | Results |
| 21 Aug 2010 | | Bow Green v Cosmopolitan Athletic | West Ham Park, Stratford | Results |
| 21 Aug 2010 | | Ford Sports Club v Asian | Fords Sports Club Ground, Newbury Park | Results |
| 21 Aug 2010 | | Goresbrook v Barking | May and Baker Annexe, Dagenham | Results |
| 21 Aug 2010 | | Hornchurch Athletic v Thurrock | Hylands Park, Hornchurch | Results |
| 21 Aug 2010 | | May and Baker v Leyton County | May and Baker Sports and Social Club Ground, Dagenham | Results |
| 28 Aug 2010 | | Asian v Bow Green | Low Hall Sports Arena, Walthamstow | Results |
| 28 Aug 2010 | | Barking v May and Baker | Mayesbrook Park, Barking | Results |
| 28 Aug 2010 | | Cosmopolitan Athletic v Hornchurch Athletic | Fairlop Oak Recreation Ground, Hainault | Results |
| 28 Aug 2010 | | Leyton County v Ford Sports Club | County Ground, Leyton | Results |
| 28 Aug 2010 | | Thurrock v Goresbrook | King George Playing Field, Grays | Results |
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