| 19 May 2010 | First Round | Middlesex Tamils v Ardleigh Green | Sudbury Hill | Results |
| 23 May 2010 | First Round | Hutton v Woodford Wells | The Polo Field Ground, Hutton | Results |
| 28 May 2010 | First Round | Ickenham v The Expatriates | Oak Avenue, Ickenham | Results |
| 31 May 2010 | First Round | North Middlesex v Waltham | North Middlesex Cricket Club Ground, Crouch End | Results |
| 04 Jun 2010 | First Round | Chipperfield Clarendon v Basingstoke and North Hants | Chipperfield Clarendon Cricket Club Ground, Tring | Results |
| 04 Jun 2010 | First Round | Old Wimbledonians v Egham | Coombe Lane, West Wimbledon | Results |
| 04 Jun 2010 | First Round | South Woodford v AJ Sports | Highfield Road, Woodford Green | Results |
| 20 Jun 2010 | First Round | Buckhurst Hill v Cambridge Granta | Roding Lane, Buckhurst Hill | Results |
| 02 Jul 2010 | Second Round | Cambridge Granta v Middlesex Tamils | Clare College Sports Ground, Cambridge | Results |
| 02 Jul 2010 | Second Round | Ickenham v East Molesey | Oak Avenue, Ickenham | Results |
| 02 Jul 2010 | Second Round | Malden Wanderers v Waltham | Cambridge Avenue, New Malden | Results |
| 02 Jul 2010 | Second Round | Shenfield v South Woodford | Chelmsford Road, Shenfield | Results |
| 02 Jul 2010 | Second Round | South Hampstead v Woodford Wells | Milverton Road, Willesden | Results |
| 02 Jul 2010 | Second Round | Southgate v Egham | John Walker's Ground, Southgate | Results |
| 02 Jul 2010 | Second Round | Walthamstow v Saffron Walden | Buck Walk, Walthamstow | Results |
| 02 Jul 2010 | Second Round | Wycombe House v Chipperfield Clarendon | Jersey Road, Osterley | Results |
| 23 Jul 2010 | Quarter-Final | Cambridge Granta v Southgate | Clare College Sports Ground, Cambridge | Results |
| 23 Jul 2010 | Quarter-Final | Wycombe House v Saffron Walden | Jersey Road, Osterley | Results |
| 01 Aug 2010 | Quarter-Final | Waltham v Ickenham | The Peter May Sports Centre, Walthamstow | Results |
| 01 Aug 2010 | Quarter-Final | Woodford Wells v Shenfield | Monkham Lane, Woodford Wells | Results |
| 30 Aug 2010 | Semi-Final | Cambridge Granta v Waltham | Clare College Sports Ground, Cambridge | Results |
| 20 Aug 2010 | Semi-Final | Wycombe House v Shenfield | Jersey Road, Osterley | Results |
| 06 Sep 2010 | Final | Shenfield v Waltham | Corfton Road, Ealing | Results |
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