| 01 Jun 1980 | First Round | Sherborne Pilgrims v Bradfield Waifs | Sherborne School, Sherborne | Results |
| 22 Jun 1980 | Second Round | Felsted Robins v Sherborne Pilgrims | Felsted School Ground, Dunmow | Results |
| 06 Jul 1980 | Quarter-Final | Sherborne Pilgrims v Charterhouse Friars | Sherborne School, Sherborne | Results |
| 01 Jun 1980 | First Round | Old Cholmeleians v Downside Wanderers | Highgate School Ground, Highgate | Results |
| 01 Jun 1980 | First Round | Old Wykehamists v Oundle Rovers | Ridding Field, Winchester | Results |
| 01 Jun 1980 | First Round | Old Whitgiftians v Rugby Meteors | Whitgift School, Croydon | Results |
| 01 Jun 1980 | First Round | Shrewsbury Saracens v Uppingham Rovers | Shrewsbury School, Shrewsbury | Results |
| 01 Jun 1980 | First Round | Stowe Templars v St Edward's Martyrs | Stowe School Ground, Stowe | Results |
| 01 Jun 1980 | First Round | Old Merchant Taylors v Old Cliftonians | Durrants Sports Ground, Croxley Green | Results |
| 01 Jun 1980 | First Round | Old Cheltonians v Old Wellingtonians | College Ground, Cheltenham | Results |
| 01 Jun 1980 | First Round | Old Brightonians v Old Blundellians | Brighton College Ground, Brighton | Results |
| 01 Jun 1980 | First Round | Haileybury Hermits v Repton Pilgrims | Haileybury College Ground, Hertford | Results |
| 01 Jun 1980 | First Round | Lancing Rovers v Marlborough Blues | Lancing College Ground, Lancing | Results |
| 01 Jun 1980 | First Round | Harrow Wanderers v Old Tonbridgians | Harrow School Cricket Ground, Harrow-on-the-Hill | Results |
| 01 Jun 1980 | First Round | Old Westminsters v Radley Rangers | Vincent Square, Westminster | Results |
| 01 Jun 1980 | First Round | Felsted Robins v Old Amplefordians | Felsted School Ground, Dunmow | Results |
| 01 Jun 1980 | First Round | Old Malvernians v Old Alleynians | Malvern College Ground, Malvern | Results |
| 01 Jun 1980 | First Round | Eton Ramblers v Charterhouse Friars | Agar's Plough, Eton College | Results |
| 15 Jun 1980 | Second Round | Old Cholmeleians v Old Wykehamists | Highgate School Ground, Highgate | Results |
| 15 Jun 1980 | Second Round | Rugby Meteors v Shrewsbury Saracens | Rugby School Ground, Rugby | Results |
| 15 Jun 1980 | Second Round | St Edward's Martyrs v Old Merchant Taylors | St Edward's School Ground, Oxford | Results |
| 15 Jun 1980 | Second Round | Old Wellingtonians v Old Blundellians | Wellington College, Crowthorne | Results |
| 15 Jun 1980 | Second Round | Repton Pilgrims v Marlborough Blues | Repton School Ground, Repton | Results |
| 15 Jun 1980 | Second Round | Harrow Wanderers v Old Westminsters | Harrow School Cricket Ground, Harrow-on-the-Hill | Results |
| 15 Jun 1980 | Second Round | Old Malvernians v Charterhouse Friars | Malvern College Ground, Malvern | Results |
| 13 Jul 1980 | Quarter-Final (Replay) | Old Wykehamists v Shrewsbury Saracens | Ridding Field, Winchester | Results |
| 06 Jul 1980 | Quarter-Final | St Edward's Martyrs v Old Wellingtonians | St Edward's School Ground, Oxford | Results |
| 06 Jul 1980 | Quarter-Final | Marlborough Blues v Old Westminsters | Marlborough College Ground, Marlborough | Results |
| 27 Jul 1980 | Semi-Final | Shrewsbury Saracens v Old Wellingtonians | Shrewsbury School, Shrewsbury | Results |
| 27 Jul 1980 | Semi-Final | Marlborough Blues v Charterhouse Friars | Marlborough College Ground, Marlborough | Results |
| 17 Aug 1980 | Final | Marlborough Blues v Old Wellingtonians | Burton's Court, Chelsea | Results |
| 13 Jul 1980 | Quarter-Final (Replay) | Old Wellingtonians v St Edward's Martyrs | Wellington College, Crowthorne | Results |
| 06 Jul 1980 | Quarter-Final | Old Wykehamists v Shrewsbury Saracens | Ridding Field, Winchester | Results |
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