| 03 Aug 2008 | Final | Great Eccleston Second XI v Vernon Carus Second XI | Hall Lane, Great Eccleston | Results |
| 29 Jun 2008 | Semi-Final | Great Eccleston Second XI v Whittingham and Goosnargh Second XI | Hall Lane, Great Eccleston | Results |
| 29 Jun 2008 | Semi-Final | Thornton Cleveleys Second XI v Vernon Carus Second XI | Illawalla, Thornton Cleveleys | Results |
| 22 Jun 2008 | Quarter-Final | Vernon Carus Second XI v Penwortham Second XI | Factory Lane, Penwortham | Results |
| 15 Jun 2008 | Second Round | Vernon Carus Second XI v BAC-EE Preston Second XI | Factory Lane, Penwortham | Results |
| 15 Jun 2008 | Quarter-Final | New Longton Second XI v Thornton Cleveleys Second XI | Chapel Lane, New Longton | Results |
| 08 Jun 2008 | Quarter-Final | South Shore Second XI v Great Eccleston Second XI | Mad Nook, Blackpool | Results |
| 08 Jun 2008 | Quarter-Final | Garstang Second XI v Whittingham and Goosnargh Second XI | Riverside Sports Ground, Garstang | Results |
| 08 Jun 2008 | Second Round | Charnock Richard Second XI v New Longton Second XI | Mossie Close, Charnock Richard | Results |
| 25 May 2008 | First Round replay | BAC-EE Preston Second XI v Whittle-le-Woods Second XI | Riverside, Preston | Results |
| 25 May 2008 | Second Round | Garstang Second XI v Gregson Lane Second XI | Riverside Sports Ground, Garstang | Results |
| 25 May 2008 | Second Round | Fulwood and Broughton Second XI v Whittingham and Goosnargh Second XI | Highfield, Broughton | Results |
| 18 May 2008 | Second Round | Fylde Second XI v Great Eccleston Second XI | Moorland Road, Poulton-le-Fylde | Results |
| 18 May 2008 | Second Round | Norcross Second XI v Thornton Cleveleys Second XI | HASRA Sports Ground, Thornton Cleveleys | Results |
| 28 May 2008 | Second Round | South Shore Second XI v Withnell Fold Second XI | Mad Nook, Blackpool | Results |
| 28 May 2008 | Second Round | Penwortham Second XI v Longridge Second XI | Middleforth Green, Penwortham | Results |
| 18 May 2008 | First Round replay | Gregson Lane Second XI v Hoghton Second XI | Gregson Lane, Hoghton | Results |
| 18 May 2008 | First Round | Eccleston Second XI v New Longton Second XI | Doctor's Lane, Eccleston | Results |
| 18 May 2008 | First Round | White Coppice Second XI v Whittingham and Goosnargh Second XI | The Green, White Coppice | Results |
| 18 May 2008 | First Round replay | Kirkham and Wesham Second XI v Fulwood and Broughton Second XI | Woodlands Avenue, Kirkham | Results |
| 11 May 2008 | First Round | Charnock Richard Second XI v Freckleton Second XI | Mossie Close, Charnock Richard | Results |
| 11 May 2008 | First Round | Thornton Cleveleys Second XI v Grimsargh Second XI | Illawalla, Thornton Cleveleys | Results |
| 11 May 2008 | First Round replay | Kirkham and Wesham Second XI v Fulwood and Broughton Second XI | Woodlands Avenue, Kirkham | Results |
| 11 May 2008 | First Round | Torrisholme Second XI v Great Eccleston Second XI | Boundary Meadow, Torrisholme | Results |
| 11 May 2008 | First Round replay | Hoghton Second XI v Gregson Lane Second XI | Hoghton Recreation Ground, Hoghton | Results |
| 04 May 2008 | First Round | Vernon Carus Second XI v Croston Second XI | Factory Lane, Penwortham | Results |
| 27 Apr 2008 | First Round | BAC-EE Preston Second XI v Whittle-le-Woods Second XI | Riverside, Preston | Results |
| 27 Apr 2008 | First Round | Hoghton Second XI v Gregson Lane Second XI | Hoghton Recreation Ground, Hoghton | Results |
| 27 Apr 2008 | First Round | Kirkham and Wesham Second XI v Fulwood and Broughton Second XI | Woodlands Avenue, Kirkham | Results |
| 27 Apr 2008 | First Round | South Shore Second XI v Harris Park Second XI | Mad Nook, Blackpool | Results |
| 27 Apr 2008 | First Round | Wrea Green Second XI v Penwortham Second XI | The Green, Wrea Green | Results |
| 27 Apr 2008 | First Round | Norcross Second XI v Walton-le-Dale Second XI | HASRA Sports Ground, Thornton Cleveleys | Results |
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